DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment scpr-B and CRISPLD1

DIOPT Version :9

Sequence 1:	NP_650061.1	Gene:	scpr-B / 41357	FlyBaseID:	FBgn0037888	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_113649.1	Gene:	CRISPLD1 / 83690	HGNCID:	18206	Length:	500	Species:	Homo sapiens

Alignment Length:	226	Identity:	53/226 - (23%)
Similarity:	80/226 - (35%)	Gaps:	50/226 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 ILNLFNELRNNVAGGKIEGLPKAVRMAKMSWCEELSHLALLNVKTCESLPDKC----RSTERFAY 120
            ||:|.|:||:.|       .|.|..|..|:|..||.       ::.||..:.|    ........
Human    65 ILDLHNKLRSQV-------YPTASNMEYMTWDVELE-------RSAESWAESCLWEHGPASLLPS 115

  Fly   121 AGQNNALFQYSGAETEYTDAEIIKEQIENWFAERSNAS----PEILASFPEELPNKAVTKFTIAV 181
            .|||  |..:.|.....|      ..:::|:.|..:.|    .|.....|........|.:|..|
Human   116 IGQN--LGAHWGRYRPPT------FHVQSWYDEVKDFSYPYEHECNPYCPFRCSGPVCTHYTQVV 172

  Fly   182 AEKNTHVGCAA-VRFSRDFYNHF-----VLTCNFA-TSNIVGQPVYTPGEKATTGCKNRYGAAYD 239
            ...:..:|||. :..:.:.:...     .|.||:: ..|..|...|..| :..:.|...:|...
Human   173 WATSNRIGCAINLCHNMNIWGQIWPKAVYLVCNYSPKGNWWGHAPYKHG-RPCSACPPSFGGGC- 235

  Fly   240 YPNLCY---------AKEIYDNEKVIENTQT 261
            ..||||         .:|...||  ||..|:
Human   236 RENLCYKEGSDRYYPPREEETNE--IERQQS 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scpr-B	NP_650061.1	SCP_euk	58..210	CDD:240180	37/163 (23%)
CRISPLD1	NP_113649.1	SCP_euk	63..207	CDD:240180	37/163 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	254..281		5/13 (38%)
		LCCL	291..375	CDD:128866
		LCCL	392..483	CDD:128866
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151154
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.850