DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment scpr-B and vap-2

DIOPT Version :9

Sequence 1:	NP_650061.1	Gene:	scpr-B / 41357	FlyBaseID:	FBgn0037888	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_001300377.1	Gene:	vap-2 / 181273	WormBaseID:	WBGene00011462	Length:	507	Species:	Caenorhabditis elegans

Alignment Length:	253	Identity:	52/253 - (20%)
Similarity:	85/253 - (33%)	Gaps:	77/253 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 CALP--TCLDKHIACNNKGNF--SENCPKDV-REVKIEPHHKLILNLFNELRNNVA------GGK 75
            |.:|  .|....:..::.|:|  ..:...|| |...:|.|        |..|:.:|      |..
Worm   284 CLVPEGLCQAPSMVKDDGGSFQCDNSLVSDVTRNFTLEQH--------NFYRSRLAKGFEWNGET 340

  Fly    76 IEGLPKAVRMAKMSWCEELSHLALLNVKTCESLPDKCRSTERFAYAGQNNALFQYSG-------A 133
            ....|||.:|.||.:                    .| ..||||....||.:|.:|.       .
Worm   341 NTSQPKASQMIKMEY--------------------DC-MLERFAQNWANNCVFAHSAHYERPNQG 384

  Fly   134 ETEYTDA-------EIIKEQIENWFAERSN-ASPEILASFPE--ELPNKAVTKFTIAVAEKNTHV 188
            :..|..:       .:|...:|.|:.|... .:|......||  :|..||:..:|....::...:
Worm   385 QNLYMSSFSNPDPRSLIHTAVEKWWQELEEFGTPIDNVLTPELWDLKGKAIGHYTQMAWDRTYRL 449

  Fly   189 GCAAVRFSRDFYNHFVLTCNFATSN--------IVGQ--------PVYTPGEKATTGC 230
            ||......:..|    :.|::..:.        .:|.        |:.|..||.|:.|
Worm   450 GCGIANCPKMSY----VVCHYGPAGNRKNNKIYEIGDPCEVDDDCPIGTDCEKTTSLC 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scpr-B	NP_650061.1	SCP_euk	58..210	CDD:240180	35/174 (20%)
vap-2	NP_001300377.1	SCP	104..253	CDD:214553
vap-2	NP_001300377.1	SCP	315..468	CDD:214553	38/185 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920