DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment scpr-B and GLIPR1L2

DIOPT Version :9

Sequence 1:	NP_650061.1	Gene:	scpr-B / 41357	FlyBaseID:	FBgn0037888	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_001257325.1	Gene:	GLIPR1L2 / 144321	HGNCID:	28592	Length:	344	Species:	Homo sapiens

Alignment Length:	179	Identity:	43/179 - (24%)
Similarity:	69/179 - (38%)	Gaps:	46/179 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 LNLFNELRNNVAGGKIEGLPKAVRMAKMSWCEELSHLALLNVKTCESLPDKCRSTE--------- 116
            :||.||||.:|       :|:...:..|:|...||       :|..:...||..|.
Human    58 VNLHNELRGDV-------IPRGSNLRFMTWDVALS-------RTARAWGKKCLFTHNIYLQDVQM 108

  Fly   117 ---RFAYAGQNNALFQYSGAETEYTDAEIIKEQIENWFAERSNASPEILASFPEELPNKAVTKFT 178
               :|...|:|    .:.|.|.|:| |.|   .|.:|.||:.      :.:|.....:...:.:.
Human   109 VHPKFYGIGEN----MWVGPENEFT-ASI---AIRSWHAEKK------MYNFENGSCSGDCSNYI 159

  Fly   179 IAVAEKNTHVGCAAVRFSRDFYNHF----VLTCNFATSNIVGQPVYTPG 223
            ..|.:.:..||||....|:  ..|.    :..||:|....:.:..|.||
Human   160 QLVWDHSYKVGCAVTPCSK--IGHIIHAAIFICNYAPGGTLTRRPYEPG 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scpr-B	NP_650061.1	SCP_euk	58..210	CDD:240180	39/164 (24%)
GLIPR1L2	NP_001257325.1	SCP_GLIPR-1_like	52..195	CDD:240185	40/166 (24%)
GLIPR1L2	NP_001257325.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	292..344
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151322
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750