DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment scpr-B and crispld2

DIOPT Version :9

Sequence 1:	NP_650061.1	Gene:	scpr-B / 41357	FlyBaseID:	FBgn0037888	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_003199065.1	Gene:	crispld2 / 100535149	ZFINID:	ZDB-GENE-130131-1	Length:	508	Species:	Danio rerio

Alignment Length:	274	Identity:	69/274 - (25%)
Similarity:	102/274 - (37%)	Gaps:	51/274 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 AIKCLILLTSLLGISLAADYCALPTCLD-KHIACNNKGNFSENCPKDVREVK----IE-PHHKLI 60
            |:..:.||  .||:||||. ..||..|: :.:....:.....|..|....|:    || ...:.|
Zfish     3 ALVSIALL--FLGVSLAAS-LFLPDSLELRQLMQRYQEELEPNSTKPDAPVRTRRAIEWSDREEI 64

  Fly    61 LNLFNELRNNVAGGKIEGLPKAVRMAKMSWCEELSHLALLNVKTCESLPDKCR----STERFAYA 121
            |.|.|:||..|       .|.|..|..|.|.:||.       ::..|..::|:    ..:.....
Zfish    65 LKLHNKLRGEV-------YPTASNMEYMIWDDELE-------RSATSWAEQCQWEHGPQDLLMSI 115

  Fly   122 GQNNALFQYSGAETEYTDAEIIKEQIENWFAE-RSNASP---EILASFPEELPNKAVTKFTIAVA 182
            |||.|:.........|        .::.|:.| :....|   |.....||.......|.:|..|.
Zfish   116 GQNLAVHWGRYRSPAY--------HVQAWYDEVKDYTYPYPHECNPWCPERCSGPMCTHYTQLVW 172

  Fly   183 EKNTHVGCAAVRFSR------DFYNHFVLTCNFA-TSNIVGQPVYTPGEKATTGCKNRYGAAYDY 240
            .....||||.....|      .:.|...|.||:: ..|.:|:..|..| :..:.|...||... .
Zfish   173 ATTNRVGCAVHVCPRMNVWGEIWENAVYLVCNYSPKGNWIGEAPYQHG-RPCSQCPPSYGGVC-R 235

  Fly   241 PNLCYAKEIYDNEK 254
            .||||.:   |:|:
Zfish   236 DNLCYKR---DSER 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scpr-B	NP_650061.1	SCP_euk	58..210	CDD:240180	39/165 (24%)
crispld2	XP_003199065.1	SCP_euk	61..206	CDD:240180	39/166 (23%)
		LCCL	299..382	CDD:128866
		LCCL	402..495	CDD:281766
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170585812
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.850