DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31388 and CG17806

DIOPT Version :9

Sequence 1:	NP_650060.1	Gene:	CG31388 / 41355	FlyBaseID:	FBgn0051388	Length:	446	Species:	Drosophila melanogaster
Sequence 2:	NP_650658.1	Gene:	CG17806 / 42142	FlyBaseID:	FBgn0038548	Length:	421	Species:	Drosophila melanogaster

Alignment Length:	476	Identity:	118/476 - (24%)
Similarity:	174/476 - (36%)	Gaps:	112/476 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRYICRTCSRMADPAVAKNLFDPSSSSVLRQIETLTNLQLKEDGKLPRFMCQDCQHDLQIAIDFR 65
            |..:||||.:.|:.  ||:|||..:..||..|..||...|:....:|..:|..|..||..||.||
  Fly     1 MTTLCRTCGQEAEH--AKSLFDKEARDVLSNILKLTGFWLRNQPGVPTRICLSCLLDLNDAIAFR 63

  Fly    66 RVCIEAQELLELQLRQVEKEEEAFESLAEQWLDDCPDELSNLSPVLQLNDRMDF----IFDPE-- 124
            ..||..             ....||...:|  :|...|.:......:|..|:|.    |..|:
  Fly    64 ERCIRT-------------NSSWFEKQGKQ--EDSDTETAREGGNNRLESRVDVMPISIAQPQRR 113

  Fly   125 ---PQDKNTDELASIKTTTTTEYMNAYQSV-----ASP---------QSSPELSTDSQLSNEHFD 172
               ||.....:...:||..|..|......:     ..|         :|.|:||:|..:.:.:.:
  Fly   114 RILPQRSKKVDGVPLKTVETPIYPLVVPEIPPADLVDPLRCEDPIQVKSEPQLSSDYPVESMNHE 178

  Fly   173 MGLSP-----ESEPES-----EAIDNRDTSSSHTC-----SKCGLEFENVD----ELKLHKYHLH 218
            ...|.     :.||.:     |...||....|..|     .|...:.||:|    :.|..||...
  Fly   179 EPASEMPQVMKEEPRTLQVIGEVQKNRRKPRSKGCLEECPGKDMAKIENIDSTTNKTKEEKYATR 243

  Fly   219 DIPPDTKFVCDHCDEGFRSAAALTRHCNMINLPLTHSCTKCKSQFHNHILLETHKQRCLRPPASQ 283
            :                :..||...:.      |.|..
  Fly   244 N----------------KWGAAKRAYA------LEHRL--------------------------- 259

  Fly   284 HVCHICGKHLTTAFNLKNHLVRHAGTRRHKCDQCSASFYTAAELCSHQK-THTTERPYICRYNCG 347
            :.|..|||..:...|...||.||.||:..:|.:|....:|...|..|.: .|..|.||:|:| ||
  Fly   260 YFCDQCGKTFSEKGNFNVHLRRHKGTKEFQCQECDRMEFTQHLLNLHVRIKHRGELPYVCKY-CG 323

  Fly   348 KTFRFCSARSMHERVHMDAS-KRIYQCEYCPKSYVTPSECRTHQKYHNLTRDHGCEICRISFKTA 411
            |.|..|..|..|||.|.::. .|.:.|..|.|::.|.:..:.|...|...:...||:|:..|...
  Fly   324 KRFDNCLKRLNHERNHKESPVHRPHVCSTCQKAFKTSTALKDHIVVHTGEQPFHCELCQTFFNRR 388

  Fly   412 KHYRSHLKSNAHK-TLEARAK 431
            ....:|.||..|: .:|.::|
  Fly   389 NALATHYKSKHHRLKVEEQSK 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31388	NP_650060.1	zf-AD	4..76	CDD:285071	27/71 (38%)
		C2H2 Zn finger	228..254	CDD:275368	3/25 (12%)
		C2H2 Zn finger	286..306	CDD:275368	7/19 (37%)
		C2H2 Zn finger	314..334	CDD:275368	5/20 (25%)
		C2H2 Zn finger	342..363	CDD:275368	11/20 (55%)
		C2H2 Zn finger	373..393	CDD:275368	5/19 (26%)
		C2H2 Zn finger	401..419	CDD:275368	5/17 (29%)
CG17806	NP_650658.1	zf-AD	4..76	CDD:285071	28/86 (33%)
		zf-C2H2	260..282	CDD:278523	7/21 (33%)
		C2H2 Zn finger	262..282	CDD:275368	7/19 (37%)
		C2H2 Zn finger	290..311	CDD:275368	5/20 (25%)
		COG5048	<298..>383	CDD:227381	29/85 (34%)
		C2H2 Zn finger	319..339	CDD:275368	11/20 (55%)
		C2H2 Zn finger	350..370	CDD:275368	5/19 (26%)
		ZnF_U1	375..407	CDD:197732	9/31 (29%)
		C2H2 Zn finger	378..396	CDD:275368	5/17 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	84	1.000	Inparanoid score	I1804
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.960