DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG31388 and MAZ

DIOPT Version :9

Sequence 1:NP_650060.1 Gene:CG31388 / 41355 FlyBaseID:FBgn0051388 Length:446 Species:Drosophila melanogaster
Sequence 2:NP_001036004.1 Gene:MAZ / 4150 HGNCID:6914 Length:493 Species:Homo sapiens


Alignment Length:397 Identity:86/397 - (21%)
Similarity:138/397 - (34%) Gaps:136/397 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   123 PEPQDKNTDELASIKTTTTTEYMNAYQSVASPQSSPELS----------TDSQLSNEHFDMGLSP 177
            |.|...:|.:.|::|           |..|.|...|.:|          :.:.::.......::|
Human   114 PAPAAASTVDTAALK-----------QPPAPPPPPPPVSAPAAEAAPPASAATIAAAAATAVVAP 167

  Fly   178 ES----EPESEAIDNRDTSSS-HTCSKCGLEFENVDELKLHK----------------------- 214
            .|    .|.:.|::.:..|.. :.|:.|..||:|...|:.|:                       
Human   168 TSTVAVAPVASALEKKTKSKGPYICALCAKEFKNGYNLRRHEAIHTGAKAGRVPSGAMKMPTMVP 232

  Fly   215 YHLHDIPP-----------------------------------DTKFVCDHCDEGFRSAAALTRH 244
            ..|..:|.                                   .....|:.|.:.||....|.||
Human   233 LSLLSVPQLSGAGGGGGEAGAGGGAAAVAAGGVVTTTASGKRIRKNHACEMCGKAFRDVYHLNRH 297

  Fly   245 CNMINLPLTHS------CTKCKSQFHN------HILLETHKQRCLRPPASQHVCHICGKHLTTAF 297
                  .|:||      |..|:.:|..      |:  .:|.....:|    :.|..|||..:...
Human   298 ------KLSHSDEKPYQCPVCQQRFKRKDRMSYHV--RSHDGAVHKP----YNCSHCGKSFSRPD 350

  Fly   298 NLKNHLVR-HAGTRRHKCDQCSASFYTAAELCSHQKTHTTERPYICRYNCGKTFRFCSAR-SMHE 360
            :|.:|:.: |:..|..||::|.|:|.|...|.:|...|..:.|  | :.|||  ...||. |.|.
Human   351 HLNSHVRQVHSTERPFKCEKCEAAFATKDRLRAHTVRHEEKVP--C-HVCGK--MLSSAYISDHM 410

  Fly   361 RVHMDASKRIYQCEYCPKSYVTPSECRTHQKYHNLTRDHG----------CEICRISFKT----A 411
            :||......:  ||.|.|.:.|.:..|.|     ..:|||          |::|.:..||    |
Human   411 KVHSQGPHHV--CELCNKGFTTAAYLRIH-----AVKDHGLQAPRADRILCKLCSVHCKTPAQLA 468

  Fly   412 KHYRSHL 418
            .|.::||
Human   469 GHMQTHL 475

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31388NP_650060.1 zf-AD 4..76 CDD:285071
C2H2 Zn finger 228..254 CDD:275368 8/25 (32%)
C2H2 Zn finger 286..306 CDD:275368 6/20 (30%)
C2H2 Zn finger 314..334 CDD:275368 7/19 (37%)
C2H2 Zn finger 342..363 CDD:275368 8/21 (38%)
C2H2 Zn finger 373..393 CDD:275368 7/19 (37%)
C2H2 Zn finger 401..419 CDD:275368 8/22 (36%)
MAZNP_001036004.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 59..78
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 121..146 8/35 (23%)
C2H2 Zn finger 192..212 CDD:275368 7/19 (37%)
C2H2 Zn finger 281..301 CDD:275368 8/25 (32%)
SFP1 <303..360 CDD:227516 12/62 (19%)
C2H2 Zn finger 309..329 CDD:275368 4/21 (19%)
C2H2 Zn finger 339..357 CDD:275368 6/17 (35%)
C2H2 Zn finger 368..388 CDD:275368 7/19 (37%)
C2H2 Zn finger 394..413 CDD:275368 8/21 (38%)
C2H2 Zn finger 421..437 CDD:275368 6/15 (40%)
C2H2 Zn finger 454..474 CDD:275368 6/19 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24390
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.100

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