DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31388 and CG8319

DIOPT Version :9

Sequence 1:	NP_650060.1	Gene:	CG31388 / 41355	FlyBaseID:	FBgn0051388	Length:	446	Species:	Drosophila melanogaster
Sequence 2:	NP_649920.2	Gene:	CG8319 / 41165	FlyBaseID:	FBgn0037722	Length:	383	Species:	Drosophila melanogaster

Alignment Length:	435	Identity:	108/435 - (24%)
Similarity:	171/435 - (39%)	Gaps:	85/435 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRYICRTCSRMADPAVAKNLFDP------SSSSVLRQIETLTNLQLKEDGKLPRFMCQDCQHDLQ 59
            |..:||.|...::..:  .:||.      ..:.:...::|..::||..|..:|:.||..|.||.:
  Fly     1 MEDLCRICGGASENML--GIFDDQVEEYVDGAKLAEMVKTCADVQLDPDDAMPQKMCISCVHDAR 63

  Fly    60 IAIDFRRVCIEAQELLELQLRQVEKEEEAFESLAEQWLDDCPDELSNLSPVLQLNDRMDFIFDPE 124
            .|..|:|.|.|..:...|.:            |..|.:.|.|:|             .||:|...
  Fly    64 TAYGFKRRCEENYKKFYLAI------------LNGQVIKDEPNE-------------EDFLFIEN 103

  Fly   125 PQDKNTDEL----ASIKTTTTTEYMNAYQSVASPQSSPELSTDSQLSNEHFDMGLSPESEPESEA 185
            |...|.:..    ..||.|..|.......|:.:.::..:|.:   :.|:.|
  Fly   104 PDKGNLEAKKKLNKEIKKTHQTASRTTKSSITTSRAGRQLRS---IKNQTF-------------- 151

  Fly   186 IDNRDTSSSHTCSKCGLEFEN----VDELKLHKYHLHDIPPDTKFVCDHCDEGFRSAAALTRHCN 246
                      .|..|..:|:.    :|.:|:|         ....||.:|:|.|...|.|..|..
  Fly   152 ----------KCELCIKQFKRQINLLDHMKVH---------SNSHVCQNCEERFLFKADLDNHQC 197

  Fly   247 MINLPLTHSCTKCKSQFHNHILLETHKQRCLRPPASQHVCHICGKHLTTAFNLKNHLVRHA---- 307
            ..|...|..|.:|...|.:...|::||.:.:: ..|...|..|.:..|...|||.||:.||
  Fly   198 YRNSNSTVECPECLKVFSSTQSLDSHKCKDMQ-ERSPFQCPHCQQAFTREQNLKAHLLIHAESKQ 261

  Fly   308 GTRRHKCDQCSASFYTAAELCSHQKTHTTERPYICRYNCGKTFRFCSARSMHERVHMDASKRIYQ 372
            |...|||..|...|:..:.|..|...|..|||:.|.: |...||...|..:|.|:|  ..::.||
  Fly   262 GNGPHKCSYCQTGFFNKSALKVHIHAHMGERPHACPF-CVSNFRSKQALKVHIRIH--TGEKPYQ 323

  Fly   373 CEYCPKSYVTPSECRTHQKYHNLTRDHGCEICRISFKTAKHYRSH 417
            |.:|||::...:....|::.|:..|.:.|.||...|:...|.:.|
  Fly   324 CPHCPKTFSDNNNLAKHRRRHSDERPYKCSICLQDFREKHHLKRH 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31388	NP_650060.1	zf-AD	4..76	CDD:285071	20/77 (26%)
		C2H2 Zn finger	228..254	CDD:275368	8/25 (32%)
		C2H2 Zn finger	286..306	CDD:275368	8/19 (42%)
		C2H2 Zn finger	314..334	CDD:275368	5/19 (26%)
		C2H2 Zn finger	342..363	CDD:275368	7/20 (35%)
		C2H2 Zn finger	373..393	CDD:275368	5/19 (26%)
		C2H2 Zn finger	401..419	CDD:275368	6/17 (35%)
CG8319	NP_649920.2	zf-AD	4..79	CDD:285071	20/76 (26%)
		COG5048	<153..368	CDD:227381	67/227 (30%)
		C2H2 Zn finger	153..173	CDD:275368	5/19 (26%)
		C2H2 Zn finger	179..196	CDD:275368	6/16 (38%)
		C2H2 Zn finger	207..227	CDD:275370	6/19 (32%)
		C2H2 Zn finger	236..256	CDD:275368	8/19 (42%)
		C2H2 Zn finger	268..288	CDD:275368	5/19 (26%)
		C2H2 Zn finger	296..316	CDD:275368	7/20 (35%)
		zf-H2C2_2	308..332	CDD:290200	10/25 (40%)
		zf-C2H2	322..344	CDD:278523	7/21 (33%)
		C2H2 Zn finger	324..344	CDD:275368	5/19 (26%)
		C2H2 Zn finger	352..368	CDD:275368	5/15 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24390
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010