DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31388 and ouib

DIOPT Version :9

Sequence 1:	NP_650060.1	Gene:	CG31388 / 41355	FlyBaseID:	FBgn0051388	Length:	446	Species:	Drosophila melanogaster
Sequence 2:	NP_649822.2	Gene:	ouib / 41039	FlyBaseID:	FBgn0037618	Length:	312	Species:	Drosophila melanogaster

Alignment Length:	423	Identity:	101/423 - (23%)
Similarity:	159/423 - (37%)	Gaps:	121/423 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRYICRTCSRMADPAVAKNLFDPSSSSVLRQIETLTNLQLKEDGKLPRFMCQDCQHDLQIAIDFR 65
            :..:||.|.|......:.||||..:...|:.:..::.|:|.:...:|.|||..||.:|:.|:.||
  Fly     2 LNIVCRVCGRQKICEKSLNLFDLVNRKYLKHLHMISGLRLVDLDDVPGFMCLCCQAELRSALAFR 66

  Fly    66 RVCIEAQELLELQLRQVEKEEEAFESLAEQWLDDCPDELSNLSPVLQLNDRMDFIFDPEPQDKNT 130
            ::||:.|                     .:||....|..|.               |.:..|.:
  Fly    67 KLCIKTQ---------------------TKWLTIEDDSSSG---------------DEDTNDNS- 94

  Fly   131 DELASIKTTTTTEYMNAYQSVASPQSSPELSTDSQLSNEHFDMGLSPESEPESEAIDNRDTSSSH 195
             ||.|.|.        |:......:       :.:|..|.|.:.:  |.||..:.: |||
  Fly    95 -ELESEKC--------AFSDFGKKK-------EGELVEETFQVLI--EEEPMDKTL-NRD----- 135

  Fly   196 TCSKCGLEFENVDELKLHKYHLHDIPPDTKFVCDHCDEGFRSAAALTRHCNMINLPLTHSCTKCK 260
              :|..|..:.:||         ...|..|.:                              |..
  Fly   136 --AKAQLREDGIDE---------KCVPSQKII------------------------------KVS 159

  Fly   261 SQFHNHILLETHKQRCLRPPASQHVCHICGKHLTTAFNLKNHLVRHAGTRRHKCDQCSASFYTAA 325
            ::..:.|                ::|.:||.|.|:....:.|:.:|.|.|...|..|.|.|.:|.
  Fly   160 TKLDDQI----------------YICELCGTHATSKPTFQRHMRKHRGERPFGCKDCDARFLSAG 208

  Fly   326 ELCSHQKTHTTERPYICRYNCGKTFRFCSARSMHERVHMDASKRIYQCEYCPKSYVTPSECRTHQ 390
            ||.:|.:.||.|:|:.||: |.|.:.....|.:|||.|  .:.|.|.||.|.|.:.|....:.|.
  Fly   209 ELRAHHRVHTGEQPFACRF-CEKRYVSYMGRLIHERTH--TNDRPYVCEECGKKFTTAYVLKNHM 270

  Fly   391 KYHNLTRDHGCEICRISFKTAKHYRSHLKSNAH 423
            ..|...|:..|:||..||:...|..:|.:|..|
  Fly   271 VIHTGERNFRCDICDRSFQRKAHLVTHTRSMMH 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31388	NP_650060.1	zf-AD	4..76	CDD:285071	24/71 (34%)
		C2H2 Zn finger	228..254	CDD:275368	0/25 (0%)
		C2H2 Zn finger	286..306	CDD:275368	6/19 (32%)
		C2H2 Zn finger	314..334	CDD:275368	8/19 (42%)
		C2H2 Zn finger	342..363	CDD:275368	8/20 (40%)
		C2H2 Zn finger	373..393	CDD:275368	6/19 (32%)
		C2H2 Zn finger	401..419	CDD:275368	7/17 (41%)
ouib	NP_649822.2	zf-AD	5..78	CDD:214871	25/93 (27%)
		COG5048	<158..300	CDD:227381	48/160 (30%)
		C2H2 Zn finger	169..189	CDD:275368	6/19 (32%)
		C2H2 Zn finger	197..217	CDD:275368	8/19 (42%)
		zf-H2C2_2	209..234	CDD:290200	11/25 (44%)
		C2H2 Zn finger	225..245	CDD:275368	8/20 (40%)
		zf-H2C2_2	241..262	CDD:290200	10/22 (45%)
		C2H2 Zn finger	253..273	CDD:275368	6/19 (32%)
		zf-H2C2_2	266..288	CDD:290200	6/21 (29%)
		C2H2 Zn finger	281..299	CDD:275368	7/17 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	84	1.000	Inparanoid score	I1804
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.960