DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31388 and nom

DIOPT Version :9

Sequence 1:	NP_650060.1	Gene:	CG31388 / 41355	FlyBaseID:	FBgn0051388	Length:	446	Species:	Drosophila melanogaster
Sequence 2:	NP_001262384.1	Gene:	nom / 41038	FlyBaseID:	FBgn0037617	Length:	370	Species:	Drosophila melanogaster

Alignment Length:	442	Identity:	111/442 - (25%)
Similarity:	170/442 - (38%)	Gaps:	128/442 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 ICRTC--SRMADPAVAKNLFDPSSSSVLRQIETLTNLQLKEDGKLPRFMCQDCQHDLQIAIDFRR 66
            :||.|  ||:...||  .||.|....:||:|:.:|.:.|::....|..:|..||.|||.|:.|||
  Fly     5 VCRVCGRSRLCPKAV--ELFKPGRQDILRRIQLITGILLQQIPNAPDMVCFCCQTDLQSAMIFRR 67

  Fly    67 VCIEAQELLELQLRQVEKEEEAFESLAEQWLDDCPDELSNLSPVLQLNDRMDFIFDP--EPQDKN 129
            .||..|                     ::|:           |:|| :|::....:.  ||.|.:
  Fly    68 QCILQQ---------------------KKWV-----------PLLQ-SDKVGASEEKKVEPNDPS 99

  Fly   130 TDELASIKTTTTTE-----YMNAYQSVASPQSSPELSTDSQLSNEHFDMGLSPESEPESEAIDNR 189
            |.:    |||....     .:.....|.:.:|  :.|....:..:.||..:...:||::...|
  Fly   100 TKK----KTTKRRRGRPRMPLEIVDIVVTNES--KASAGESVGGDEFDQPVEISNEPDATDSD-- 156

  Fly   190 DTSSSHTCSKCGLEFENVDELKLHKYHLHDIPPDTKFVCDHCDEGFRSAAALTRHCNMINLPLTH 254
                           .|::|:.|         ||        ::|..|
  Fly   157 ---------------VNLEEIDL---------PD--------EDGLES----------------- 172

  Fly   255 SCTKCKSQFHNHILLETHKQRCLRPPASQHVCHICGKHLTTAFNLKNHLVRHAGTRRHKCDQCSA 319
                      :|.|          |....|.|..||.......:|..|...|.|.|.:.|.:|..
  Fly   173 ----------DHDL----------PNVQIHKCDTCGIIKNNKSSLVRHQFEHNGIRPYPCKECPK 217

  Fly   320 SFYTAAELCSHQKT-HTTERPYICRYNCGKTFRFCSARSMHERVHMDASKRIYQCEYCPKSYVTP 383
            :|..|:||.:|..| ||.|.|:.||| |.:.:.....|..|||||  .::|.:.|:.|.|::...
  Fly   218 TFLVASELKAHNLTHHTLEPPFACRY-CDRRYFSVVGRKKHERVH--TNERPFVCDQCGKAFTRT 279

  Fly   384 SECRTHQKYHNLTRDHGCEICRISFKTAKHYRSHLKSNAHKTLEARAKAAAS 435
            ...:.|...|.:.|.:.|::|..||...||..:|..||.||   ..|:|..|
  Fly   280 CILKAHMAVHQVVRKYSCDVCDRSFSLKKHLATHFISNTHK---RNAEAVTS 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31388	NP_650060.1	zf-AD	4..76	CDD:285071	29/73 (40%)
		C2H2 Zn finger	228..254	CDD:275368	2/25 (8%)
		C2H2 Zn finger	286..306	CDD:275368	5/19 (26%)
		C2H2 Zn finger	314..334	CDD:275368	8/20 (40%)
		C2H2 Zn finger	342..363	CDD:275368	8/20 (40%)
		C2H2 Zn finger	373..393	CDD:275368	4/19 (21%)
		C2H2 Zn finger	401..419	CDD:275368	7/17 (41%)
nom	NP_001262384.1	zf-AD	5..76	CDD:214871	29/93 (31%)
		C2H2 Zn finger	184..204	CDD:275368	5/19 (26%)
		C2H2 Zn finger	212..261	CDD:275368	20/49 (41%)
		zf-H2C2_2	255..278	CDD:290200	9/24 (38%)
		C2H2 Zn finger	269..289	CDD:275368	4/19 (21%)
		zf-H2C2_2	282..305	CDD:290200	6/22 (27%)
		C2H2 Zn finger	297..313	CDD:275368	6/15 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	84	1.000	Inparanoid score	I1804
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.960