DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31388 and CG17359

DIOPT Version :9

Sequence 1:	NP_650060.1	Gene:	CG31388 / 41355	FlyBaseID:	FBgn0051388	Length:	446	Species:	Drosophila melanogaster
Sequence 2:	NP_648679.1	Gene:	CG17359 / 39549	FlyBaseID:	FBgn0036396	Length:	339	Species:	Drosophila melanogaster

Alignment Length:	423	Identity:	101/423 - (23%)
Similarity:	156/423 - (36%)	Gaps:	106/423 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 ICRTCSRMAD--------PAVAKNLF---DPSSSSVLRQIETLTNLQLKEDGKLPRFMCQDCQHD 57
            :||.|...:|        |..:.|..   :|..:::||:....:  ..|||| :|:|:|.:|...
  Fly     6 MCRVCRDESDCLLDIYTEPYASSNRVQEQEPVLATMLRECSGCS--VHKEDG-MPQFICVECAEA 67

  Fly    58 LQIAIDFRRVCIEAQELLELQLRQVEKEEEAFESLAEQWLDD---CPDELSNLSPVLQLNDRMDF 119
            ::.|...||.|.::.:..| |||.:.||           |||   |.:...|:.|.:.:: .|:.
  Fly    68 VRNAYRLRRQCRKSHQYFE-QLRLMMKE-----------LDDIEYCLNIGDNIEPQMPVS-VMEA 119

  Fly   120 IFDPEPQDKNTDELASIKTTTTTEYMNAYQSVASPQSSPELSTDSQLSNEH-FDMGLSPESEPES 183
            ...||..:....||..:|      ||       .|:..| :|:....:||| .....||...|.:
  Fly   120 GKTPETSEPLLVELVQVK------YM-------PPEPKP-ISSPLPDNNEHKLAQSYSPAKTPHN 170

  Fly   184 EAIDNRDTSSSHTCSKCGLEFENVDELKLHKYHLHDIPPDTKFVCDHCDEGFRSAAALTRHCNMI 248
            ::.....:.|.:.......|.|:.|:.|:........|.
  Fly   171 KSKRRARSYSDNDSWSPDSELEHEDDDKIWNASKRGKPK-------------------------- 209

  Fly   249 NLPLTHSCTKCKSQFHNHILLETHKQRCLRPPASQHVCHICGKHLTTAFNLKNHLVRHAGTRRHK 313
            .:|..:.|..|...|       |.||                       ||:.|:..|.|.|.:|
  Fly   210 RVPGPYRCKLCTQSF-------TQKQ-----------------------NLEIHMRIHTGERPYK 244

  Fly   314 CDQCSASFYTAAELCSHQKTHTTERPYICRYNCGKTFRFCSARSMHERVHMDASKRIYQCEYCPK 378
            |..|..||.....|.||.:.||.|||:.|. ||.|.||......:|.|.|  ..::.::|..|.:
  Fly   245 CSLCPRSFAQKGNLQSHTRCHTGERPFGCP-NCPKRFRQVGQLQVHTRTH--TGEQPFKCSKCQQ 306

  Fly   379 SYVTPSECRTHQKYH--NLTRDHGCEICRISFK 409
            |:...:..:.|...|  ...|....|..|..||
  Fly   307 SFKQLNGLQKHMSAHTRGKRRTSSQETKRNKFK 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31388	NP_650060.1	zf-AD	4..76	CDD:285071	21/82 (26%)
		C2H2 Zn finger	228..254	CDD:275368	1/25 (4%)
		C2H2 Zn finger	286..306	CDD:275368	3/19 (16%)
		C2H2 Zn finger	314..334	CDD:275368	7/19 (37%)
		C2H2 Zn finger	342..363	CDD:275368	8/20 (40%)
		C2H2 Zn finger	373..393	CDD:275368	4/19 (21%)
		C2H2 Zn finger	401..419	CDD:275368	4/9 (44%)
CG17359	NP_648679.1	zf-AD	6..88	CDD:285071	22/85 (26%)
		zf-C2H2	215..237	CDD:278523	9/51 (18%)
		C2H2 Zn finger	217..237	CDD:275368	9/49 (18%)
		zf-H2C2_2	229..254	CDD:290200	11/24 (46%)
		C2H2 Zn finger	245..265	CDD:275368	7/19 (37%)
		zf-H2C2_2	257..282	CDD:290200	13/25 (52%)
		C2H2 Zn finger	273..293	CDD:275368	8/20 (40%)
		zf-H2C2_2	286..310	CDD:290200	6/25 (24%)
		C2H2 Zn finger	301..321	CDD:275368	4/19 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457839
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030