DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31388 and CG15436

DIOPT Version :9

Sequence 1:	NP_650060.1	Gene:	CG31388 / 41355	FlyBaseID:	FBgn0051388	Length:	446	Species:	Drosophila melanogaster
Sequence 2:	NP_608840.1	Gene:	CG15436 / 33657	FlyBaseID:	FBgn0031610	Length:	346	Species:	Drosophila melanogaster

Alignment Length:	424	Identity:	94/424 - (22%)
Similarity:	154/424 - (36%)	Gaps:	89/424 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRYICRTCSRMADPAVAKNLFDP---SSSSVLRQIETLTNLQLKEDGKLPRFMCQDCQHDLQIAI 62
            |..|||.|..::...|  |:||.   :..|:...|...|..::|........:|..|..|::.|.
  Fly     1 MAEICRVCMDISGKLV--NIFDARRRTRVSIAEMIAQCTGFEVKRGDLFSEMICPQCYEDVKSAY 63

  Fly    63 DFRRVCIEAQELLELQLRQVEKEEEAFESLAEQWLDDCPDELSNLSPVLQLNDRMDFIFDPEPQD 127
            ..|:.|.|:.:.. .::|. |..|:|..:|.|:                            |..:
  Fly    64 GIRQTCEESHQFY-CRVRD-EGIEDALCALLEE----------------------------EDWE 98

  Fly   128 KNTDELASIKTTTTTEYMNAYQSVASPQSSPELSTDSQLSNEHFDMGLSPESEPESEAIDNRDTS 192
            .:.||.|.|.:.:..:                            |.|.|...:...|
  Fly    99 ISEDEDARIDSASAAD----------------------------DDGKSDSKKVAFE-------- 127

  Fly   193 SSHTCSKCGLEFENVDELKLH-KYHLHDIPPDTKFVCDHCDEGFRSAAALTRHCNMINLPLTHSC 256
                |.:|..:::.......| :.|:    ....|.|.:|...||....|..|....|....:.|
  Fly   128 ----CRECHKKYQRKGTFLRHMRTHM----DGQSFPCPYCKRNFRLRVTLKAHMKTHNAAKPYEC 184

  Fly   257 TKCKSQFHNHILLETHKQRCL--RPPASQHVCHICGKHLTTAFNLKNHLVRHAGTRRHKCDQCSA 319
            :.|...|.....|::|::...  ||    ..|..|.|....:.:|:.|:..|...|..||.:|:.
  Fly   185 SHCAKTFAQQSTLQSHERTHTGERP----FKCSQCSKTFIKSSDLRRHIRTHGSERPFKCSKCTK 245

  Fly   320 SFYTAAELCSHQKTHTTERPYICRYNCGKTFRFCSARSMHERVHMDASKRIYQCEYCPKSYVTPS 384
            :|.....|.:|.::||.|||:.|.: |.|.|........|.|:|:  ..|.::|.:|||::...|
  Fly   246 TFTRKFHLDNHFRSHTGERPFKCSH-CPKAFAMKQHLKQHSRLHL--PDRPFRCSHCPKTFRLSS 307

  Fly   385 ECRTHQKYHNLTRDHGCEICRISFKTAKHYRSHL 418
            ..:.|:..||..|...|..|...:|..|....|:
  Fly   308 TLKEHKLVHNAERTFKCPHCASFYKQRKTLARHI 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31388	NP_650060.1	zf-AD	4..76	CDD:285071	19/74 (26%)
		C2H2 Zn finger	228..254	CDD:275368	7/25 (28%)
		C2H2 Zn finger	286..306	CDD:275368	5/19 (26%)
		C2H2 Zn finger	314..334	CDD:275368	5/19 (26%)
		C2H2 Zn finger	342..363	CDD:275368	6/20 (30%)
		C2H2 Zn finger	373..393	CDD:275368	6/19 (32%)
		C2H2 Zn finger	401..419	CDD:275368	5/18 (28%)
CG15436	NP_608840.1	zf-AD	4..78	CDD:285071	19/76 (25%)
		C2H2 Zn finger	128..148	CDD:275368	3/19 (16%)
		C2H2 Zn finger	156..176	CDD:275368	6/19 (32%)
		COG5048	<180..341	CDD:227381	46/167 (28%)
		C2H2 Zn finger	184..204	CDD:275368	5/19 (26%)
		zf-H2C2_2	197..219	CDD:290200	7/25 (28%)
		C2H2 Zn finger	212..232	CDD:275368	5/19 (26%)
		zf-H2C2_2	224..249	CDD:290200	8/24 (33%)
		C2H2 Zn finger	240..260	CDD:275368	5/19 (26%)
		zf-H2C2_2	252..276	CDD:290200	10/24 (42%)
		C2H2 Zn finger	268..288	CDD:275368	6/20 (30%)
		C2H2 Zn finger	296..316	CDD:275368	6/19 (32%)
		C2H2 Zn finger	324..341	CDD:275368	4/16 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	84	1.000	Inparanoid score	I1804
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.150