DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31388 and CG31441

DIOPT Version :9

Sequence 1:	NP_650060.1	Gene:	CG31388 / 41355	FlyBaseID:	FBgn0051388	Length:	446	Species:	Drosophila melanogaster
Sequence 2:	NP_731558.1	Gene:	CG31441 / 326139	FlyBaseID:	FBgn0051441	Length:	341	Species:	Drosophila melanogaster

Alignment Length:	444	Identity:	111/444 - (25%)
Similarity:	179/444 - (40%)	Gaps:	120/444 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRYICRTCSRMAD--PAVAKNLFDPSSSSVLRQIETLTNLQLKEDGKLPRFMCQDCQHDLQIAID 63
            :|.|||||.:...  ...|..||:.|:...:..:|.:|::.|:.|..||..:||.|:..|...:.
  Fly     4 LRSICRTCGKNVTNLQGRATKLFNKSNYHFISILENITDMYLEFDTTLPHLICQCCKVQLDRILT 68

  Fly    64 FRRVCIEAQELLELQLRQVEKEEEAFESLAEQWLDDCPDELSNLSPVLQLNDRMDFIFDPEPQD- 127
            ||..|:|..:......|::.::    :::.::.||. ||       |.:|.           ||
  Fly    69 FRNKCLEVHKSFMAANRKLLRK----KAIVDEELDK-PD-------VEKLQ-----------QDL 110

  Fly   128 -KNTDELASIKTTTTTEYMNAYQSVASPQSSPELSTDSQLSNEHFDMGLSPESEPESE-AIDNRD 190
             .:||:...:....|.                               ||..|...::| |.|..|
  Fly   111 WDHTDQEMCVAMADTA-------------------------------GLLREDHNDNEKAKDAED 144

  Fly   191 TSSSHTCSKCGLEFENVDELKLHKYHLHDIPPDTKFVCDHCDEGFRSAAALTRHCNMINLPLTHS 255
            .:.:.         :|.:|         .:...|:.| :||.|
  Fly   145 ATQNE---------KNQEE---------QVQVQTEEV-EHCQE---------------------- 168

  Fly   256 CTKCKSQFHNHILLETHKQRCLRPP------ASQHVCHICGKHLTTAFNLKNHLVRHAGTRRHKC 314
                  |.||..::.  |....|.|      :....|..||....::..||.||.||:|.:...|
  Fly   169 ------QLHNMSIIS--KGVSARVPKRTKRNSKSWFCDQCGGVFKSSTYLKLHLQRHSGHKPFAC 225

  Fly   315 DQCSASFYTAAELCSHQKTHTTERPYICRYNCGKTFRFCSARSMHERVHMDASKRIYQCEYCPKS 379
            |.|.|.:||..|:..|:..||..|||.||: |.||:|.||::.:|||.|  .::|.:||::|.|:
  Fly   226 DICQAKYYTDNEMRRHRILHTDARPYACRF-CSKTYRGCSSKVVHERTH--TNERPFQCQHCDKA 287

  Fly   380 YVTPSECRTHQKYHNLTRDHGCEICRISFKTAKHYRSHLKSNAHKTLEARAKAA 433
            :.:.|..:.|:..|...|.:.||||...|..:.|...|..:..|   :.||::|
  Fly   288 FTSTSTRQKHEMLHTNQRKYHCEICDQWFLRSSHLTLHQSTKLH---QRRAESA 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31388	NP_650060.1	zf-AD	4..76	CDD:285071	23/73 (32%)
		C2H2 Zn finger	228..254	CDD:275368	3/25 (12%)
		C2H2 Zn finger	286..306	CDD:275368	7/19 (37%)
		C2H2 Zn finger	314..334	CDD:275368	8/19 (42%)
		C2H2 Zn finger	342..363	CDD:275368	11/20 (55%)
		C2H2 Zn finger	373..393	CDD:275368	5/19 (26%)
		C2H2 Zn finger	401..419	CDD:275368	7/17 (41%)
CG31441	NP_731558.1	zf-AD	7..82	CDD:285071	23/74 (31%)
		COG5048	<174..337	CDD:227381	57/170 (34%)
		C2H2 Zn finger	197..217	CDD:275370	7/19 (37%)
		C2H2 Zn finger	225..245	CDD:275368	8/19 (42%)
		C2H2 Zn finger	253..273	CDD:275368	11/20 (55%)
		zf-H2C2_2	268..290	CDD:290200	9/23 (39%)
		C2H2 Zn finger	281..301	CDD:275368	5/19 (26%)
		C2H2 Zn finger	309..328	CDD:275368	7/18 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439345
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	84	1.000	Inparanoid score	I1804
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.980