DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31388 and ace2

DIOPT Version :9

Sequence 1:	NP_650060.1	Gene:	CG31388 / 41355	FlyBaseID:	FBgn0051388	Length:	446	Species:	Drosophila melanogaster
Sequence 2:	NP_594109.1	Gene:	ace2 / 2541661	PomBaseID:	SPAC6G10.12c	Length:	533	Species:	Schizosaccharomyces pombe

Alignment Length:	399	Identity:	87/399 - (21%)
Similarity:	131/399 - (32%)	Gaps:	149/399 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 EEAFESL---AEQWLD--------------DCP----------DELSNL--------------SP 109
            ::||..:   |..|:|              |.|          |.|.|.              |.
pombe   148 QQAFSEIGYDASNWIDELDSQQQVLSFPEFDIPEIKTETCSNKDHLENFDYLSSSIPETSGPASS 212

  Fly   110 VL----QLNDRMDFIFDPEPQDKNTDELASIKTTTTTEYMNAYQSVASPQSSPELSTDSQLSNEH 170
            ||    ||....:|:|.|    .:...|..|....:.|.:|...|..||....:||:.....|
pombe   213 VLPSSSQLESFNEFMFLP----SSPPGLDEINGAPSFEELNFQISQPSPAHPVDLSSPETAPN-- 271

  Fly   171 FDMGLSPES--------EPESE-----AIDN--------RDTSSSHTCSKCGLEFENVDELKLHK 214
                :||.|        ||.|.     |:|:        |.|.:....:|.....|.|.|.:
pombe   272 ----ISPVSPFAQLVKLEPTSPQKPSFALDSSFSHLDVCRHTDNQKAFAKLSSPAEYVSEFE--- 329

  Fly   215 YHLHDIPPDTKF--VCDH------------CDEGFRSAA---------------------ALTRH 244
                      ||  ||||            ..:.|..:|                     .|...
pombe   330 ----------KFSSVCDHGLDISNANINNTLTQQFALSAPYESCIVTKKPEPCITVKEEEQLAPK 384

  Fly   245 CNMINLPLTHSCTKCKSQ-----FHNHILLETHKQR---CLRPPAS------------QHVC--H 287
            ....:|.:|...|:..|:     .::| ..:|.||.   |..||.:            ::||  :
pombe   385 IESADLSITPQVTEHDSKPPVRISYDH-RCKTRKQSTRICRIPPETMASLYCGPEADGKYVCLYN 448

  Fly   288 ICGKHLTTAFNLKNHLVRHAGTRRHKCDQCSASFYTAAELCSHQKTHTTERPYICRYNCGKTFRF 352
            .|.|.:...:|:::|:..|...|.::||.|.|.|....:|..|.:.|...|||:|  .|.|.|..
pombe   449 GCNKRIARKYNVESHIQTHLSDRPYRCDLCKAGFVRHHDLKRHLRIHENGRPYVC--ECLKRFNR 511

  Fly   353 CSARSMHER 361
            ..|.:.|::
pombe   512 LDALNRHKQ 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31388	NP_650060.1	zf-AD	4..76	CDD:285071
		C2H2 Zn finger	228..254	CDD:275368	7/58 (12%)
		C2H2 Zn finger	286..306	CDD:275368	5/21 (24%)
		C2H2 Zn finger	314..334	CDD:275368	7/19 (37%)
		C2H2 Zn finger	342..363	CDD:275368	6/20 (30%)
		C2H2 Zn finger	373..393	CDD:275368
		C2H2 Zn finger	401..419	CDD:275368
ace2	NP_594109.1	COG5048	45..518	CDD:227381	86/395 (22%)
		C2H2 Zn finger	448..467	CDD:275368	4/18 (22%)
		zf-C2H2	473..495	CDD:278523	7/21 (33%)
		C2H2 Zn finger	475..495	CDD:275368	7/19 (37%)
		zf-H2C2_2	487..511	CDD:290200	10/25 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	84	1.000	Inparanoid score	I1804
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050