DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31388 and F58G1.2

DIOPT Version :9

Sequence 1:	NP_650060.1	Gene:	CG31388 / 41355	FlyBaseID:	FBgn0051388	Length:	446	Species:	Drosophila melanogaster
Sequence 2:	NP_001254358.1	Gene:	F58G1.2 / 174931	WormBaseID:	WBGene00010264	Length:	500	Species:	Caenorhabditis elegans

Alignment Length:	482	Identity:	111/482 - (23%)
Similarity:	163/482 - (33%)	Gaps:	148/482 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 RTCSRMADPAVAKNLFDPSS---SSVLRQIETLTNLQLKEDGKLPRFMCQD-CQHDL------QI 60
            |...::.:...|.|..|||:   ..::||.:                  || |..||      .:
Worm   107 RPIKKLRENRAALNFIDPSAELDKCIVRQKQ------------------QDFCAPDLNMVPASSL 153

  Fly    61 AID----------FR-RVC---IEAQELLELQLRQVEKEEEAFESLAEQWLDDCPDELSNLSPVL 111
            :||          || :||   .....|||..||  :...:|:.:..|
Worm   154 SIDEIRNAVRKSMFRCKVCKNRFGEMSLLERHLR--DSHPKAYIAFLE----------------- 199

  Fly   112 QLNDR--MDFIFDPEPQDKNTDELASIKTTTTTEYMNAYQSVASPQS-----SPELSTDS-QLSN 168
              |.|  .|::.:.|.:....:||.|             .....|:|     |..|..|| .|..
Worm   200 --NQREMADYMGELERERNRIEELVS-------------GGFIPPESEIEATSNNLEVDSIPLPG 249

  Fly   169 EHFDMGLSPESEPESEAIDNRDT---------SSSHTCSKCGLEFENVDELKLHKYHLHDIPPDT 224
            |: ..|..|........:...|.         ..|..|..|...|.|......|....|  |...
Worm   250 EN-SQGHIPRLNRYGGLMYPMDALRKKFPYLKKRSPQCPFCDKRFRNDISFNNHLTKKH--PECA 311

  Fly   225 KFV-CDHCDEGFRSAAALTRH-CNMINLPLTHSCTKCKSQFHNHILLETHKQRCLRPPASQHVCH 287
            :|| |.||.:...|||.|..| |:     ||:.|..|                  ||     :.:
Worm   312 EFVQCLHCFKCLPSAADLPTHDCD-----LTYLCLDC------------------RP-----IRN 348

  Fly   288 ICGKHLTTAFNLKNHLVRHAGTRRHKCDQCSASFYTAAELCSHQK-THTTERPYICRYNCGKTFR 351
            :|..:.......|.|...|:|.|   |..|:..|.|..:|..|:| .|...|.:.|.: |.:.|.
Worm   349 MCNGYRLFRHRTKFHRGYHSGFR---CPDCNQKFLTPRKLRKHRKMAHVFSRTFQCHF-CEEFFI 409

  Fly   352 FCSARSMHERVHMDASKRIYQCEYC---PKSYVTPSECRTHQKYHNLTRDHG--CEICRISFKTA 411
            ..:|.::|||||....|  ::|..|   ...|:...|   |.|.|     ||  |.:|::..:..
Worm   410 SDTAVTIHERVHTGILK--FECTVCDFRASRYLQMEE---HTKEH-----HGYMCSVCQLKCQHW 464

  Fly   412 KHYRSHL--KSNAHKTLEARAKAAASP 436
            ...:.|:  :.:.:.|.||......||
Worm   465 NDIKDHMLAEHSCYVTEEASQVYIESP 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31388	NP_650060.1	zf-AD	4..76	CDD:285071	20/93 (22%)
		C2H2 Zn finger	228..254	CDD:275368	10/26 (38%)
		C2H2 Zn finger	286..306	CDD:275368	3/19 (16%)
		C2H2 Zn finger	314..334	CDD:275368	7/20 (35%)
		C2H2 Zn finger	342..363	CDD:275368	7/20 (35%)
		C2H2 Zn finger	373..393	CDD:275368	6/22 (27%)
		C2H2 Zn finger	401..419	CDD:275368	3/19 (16%)
F58G1.2	NP_001254358.1	bZIP	<186..222	CDD:304365	9/56 (16%)
		C2H2 Zn finger	372..393	CDD:275368	7/20 (35%)
		C2H2 Zn finger	401..421	CDD:275368	7/20 (35%)
		C2H2 Zn finger	429..449	CDD:275368	6/22 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000