DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31388 and Snai1

DIOPT Version :9

Sequence 1:	NP_650060.1	Gene:	CG31388 / 41355	FlyBaseID:	FBgn0051388	Length:	446	Species:	Drosophila melanogaster
Sequence 2:	NP_446257.1	Gene:	Snai1 / 116490	RGDID:	620758	Length:	264	Species:	Rattus norvegicus

Alignment Length:	273	Identity:	62/273 - (22%)
Similarity:	104/273 - (38%)	Gaps:	62/273 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 QLNDR-MDFIFDPEPQDKNTDELASIKTTTTTEYMN--------AYQSVASPQ------------ 155
            :|.|. ::|.|. :|.|: ...||:|   ...|.:|        .:.|:..||
  Rat    21 ELQDACVEFTFQ-QPYDQ-AHLLAAI---PPPEVLNPAASLPTLIWDSLLVPQVQPVAWATLPLR 80

  Fly   156 SSPELSTDSQLSNEHFDMGLSPESEPESEAIDNRDTSSSHTCSKCGLEFENVDEL--KLHKYHLH 218
            .||..:..:.||:|.......|.|.|.........||:|...::..:.|..:.:|  :|.:..:.
  Rat    81 ESPRAAELTSLSDEDSGKSSQPPSPPSPAPSSFSSTSASSLEAEAFIAFPGLGQLPKQLARLSVA 145

  Fly   219 DIPPDTK-FVCDHCDEGFRSAAALTRHCNMINLPLTHSCTKCKSQFHNHILLETHKQRCLRPPAS 282
            ..|...| |.|.:|::.:.|..||..|                        :.:|...|
  Rat   146 KDPQSRKAFNCKYCNKEYLSLGALKMH------------------------IRSHTLPC------ 180

  Fly   283 QHVCHICGKHLTTAFNLKNHLVRHAGTRRHKCDQCSASFYTAAELCSHQKTHTTERPYICRYNCG 347
              ||..|||..:..:.|:.|:..|.|.:...|..|:.:|...:.|.:|.:||:..:.|.|: .|.
  Rat   181 --VCTTCGKAFSRPWLLQGHVRTHTGEKPFSCSHCNRAFADRSNLRAHLQTHSDVKRYQCQ-ACA 242

  Fly   348 KTFRFCSARSMHE 360
            :||...|....|:
  Rat   243 RTFSRMSLLHKHQ 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31388	NP_650060.1	zf-AD	4..76	CDD:285071
		C2H2 Zn finger	228..254	CDD:275368	6/25 (24%)
		C2H2 Zn finger	286..306	CDD:275368	6/19 (32%)
		C2H2 Zn finger	314..334	CDD:275368	5/19 (26%)
		C2H2 Zn finger	342..363	CDD:275368	6/19 (32%)
		C2H2 Zn finger	373..393	CDD:275368
		C2H2 Zn finger	401..419	CDD:275368
Snai1	NP_446257.1	C2H2 Zn finger	156..176	CDD:275368	6/43 (14%)
		COG5048	<177..>253	CDD:227381	23/84 (27%)
		zf-C2H2	180..202	CDD:278523	8/29 (28%)
		C2H2 Zn finger	182..202	CDD:275368	6/19 (32%)
		zf-H2C2_2	195..218	CDD:290200	6/22 (27%)
		zf-C2H2	208..230	CDD:278523	5/21 (24%)
		C2H2 Zn finger	210..230	CDD:275368	5/19 (26%)
		C2H2 Zn finger	238..255	CDD:275368	5/17 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24390
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100