DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arfip and Arfip1

DIOPT Version :9

Sequence 1:	NP_650058.1	Gene:	Arfip / 41353	FlyBaseID:	FBgn0037884	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	XP_006232601.1	Gene:	Arfip1 / 60382	RGDID:	708401	Length:	373	Species:	Rattus norvegicus

Alignment Length:	365	Identity:	161/365 - (44%)
Similarity:	225/365 - (61%)	Gaps:	52/365 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 SGILGSAS--------SHSIAGGGG---------GGGNVGVGV---GGPFGAPSSLPLRNHSAPT 77
            :|.:|.|.        .||:..|.|         |..:...||   |...|:         |||.
  Rat    18 NGEVGDAHEHGYNRDLKHSLPSGLGLSETQITSHGFDSTKEGVTEAGASQGS---------SAPP 73

  Fly    78 TP--MSPS--------------SPPSGNGILSPTDSG----SGSIIRTSASKIDSLKNWSISTYK 122
            .|  :|||              :.|:| |..:.|..|    :..|...:..|::.::.||::|||
  Rat    74 LPCVLSPSRVAASQLTQHAGDLTVPAG-GQRTHTKGGPVILADEIKNPAMEKLELVRKWSLNTYK 137

  Fly   123 CTRQIMLEKLGKSQRTVDSELEAQIEQLRETQRKYLSILRLTRAFSSHFQHVVVTQHALADSFAD 187
            |||||:.||||:..||||.||||||:.||:.::||.:||:|.:..|:....:|.||..|.|:|||
  Rat   138 CTRQIISEKLGRGSRTVDLELEAQIDILRDNKKKYENILKLAQTLSTQLFQMVHTQKQLGDAFAD 202

  Fly   188 LAQKNPELQKEFTCNSETQRNLTKNGELLLNALNFFISSVNTLCNKTIDDTLLTIRQYETARIEF 252
            |:.|:.||.:||..|::||:.|.||||.||.|:||||:|||||.||||:|||:|::|||.||||:
  Rat   203 LSLKSLELHEEFGYNADTQKLLAKNGETLLGAINFFIASVNTLVNKTIEDTLMTVKQYENARIEY 267

  Fly   253 DAYRMDLE--NTKPELTPSAVALEETQRSYAQHKEQYEKLRSDVAVKMQFLDENRIKVMHKQLIL 315
            ||||.|||  |..|....:...:|::|..:..|||:|:|:||||:||::||:||::||:..||.|
  Rat   268 DAYRTDLEELNLGPRDANTLPKIEQSQHLFQIHKEKYDKMRSDVSVKLKFLEENKVKVLRNQLAL 332

  Fly   316 LHNAIAAYFSGNAMALESTLKQFNIKLKSPNAVTGSWLEQ 355
            .|:|:||||:||...||.|||||::|||:|.....||||:
  Rat   333 FHSAVAAYFAGNQKQLEQTLKQFHVKLKTPGVDAPSWLEE 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arfip	NP_650058.1	BAR_Arfaptin	140..338	CDD:153344	108/199 (54%)
Arfip1	XP_006232601.1	BAR_Arfaptin	155..355	CDD:153344	108/199 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335313
Domainoid	1	1.000	267	1.000	Domainoid score	I1799
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	305	1.000	Inparanoid score	I2558
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1179170at2759
OrthoFinder	1	1.000	-	-		FOG0003325
OrthoInspector	1	1.000	-	-		otm46197
orthoMCL	1	0.900	-	-		OOG6_105484
Panther	1	1.100	-	-	O	PTHR12141
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2693
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.900