Protein Alignment Arfip and ARFIP2

DIOPT Version :10

• Sequence 1: NP_650058.1
• Gene: Arfip / 41353
• FlyBaseID: FBgn0037884
• Length: 355
• Species: Drosophila melanogaster
• Sequence 2: NP_001229783.1
• Gene: ARFIP2 / 23647
• HGNCID: 17160
• Length: 374
• Species: Homo sapiens
• Alignment Length: 364
• Identity: 169/364 - (46%)
• Similarity: 235/364 - (64%)
• Gaps: 35/364 - (9%)

  Fly     5 ERSIHEMLKDAPSLNDSCGAVHTGTEGGS--GILGSASSHSIAGGGGGGG---------NVGVGV 58
            |:.:.:::...|:||::  ::.:|..|||  |::.:..|.|.|......|         ..||..
Human    32 EQDLQQVMVSGPNLNET--SIVSGGYGGSGDGLIPTGKSISCARREVWVGPQRCLVYLREAGVRE 94

  Fly    59 GGPFGAPSSLPLRNHSAPTTPMSPSSPPSGNGILSPTDSGSGSIIRTSASKIDSLKNWSISTYKC 123
            ..|.|:.     |:.|..|||..|....: .||              :..|.|.:|.|.|:||||
Human    95 LDPLGSG-----RHPSHSTTPSGPGDEVA-RGI--------------AGEKFDIVKKWGINTYKC 139

  Fly   124 TRQIMLEKLGKSQRTVDSELEAQIEQLRETQRKYLSILRLTRAFSSHFQHVVVTQHALADSFADL 188
            |:|::.|:.|:..||||.|||.|||.||||:|||.|:|:|.||.::|...::.|||||.|:||||
Human   140 TKQLLSERFGRGSRTVDLELELQIELLRETKRKYESVLQLGRALTAHLYSLLQTQHALGDAFADL 204

  Fly   189 AQKNPELQKEFTCNSETQRNLTKNGELLLNALNFFISSVNTLCNKTIDDTLLTIRQYETARIEFD 253
            :||:||||:||..|:|||:.|.||||.||.|:|||:||:|||..||::|||:|::|||.||:|:|
Human   205 SQKSPELQEEFGYNAETQKLLCKNGETLLGAVNFFVSSINTLVTKTMEDTLMTVKQYEAARLEYD 269

  Fly   254 AYRMDLENTK--PELTPSAVALEETQRSYAQHKEQYEKLRSDVAVKMQFLDENRIKVMHKQLILL 316
            |||.|||...  |....:...||..|.::..|:::|||||.|||:|::||:||:||||||||:|.
Human   270 AYRTDLEELSLGPRDAGTRGRLESAQATFQAHRDKYEKLRGDVAIKLKFLEENKIKVMHKQLLLF 334

  Fly   317 HNAIAAYFSGNAMALESTLKQFNIKLKSPNAVTGSWLEQ 355
            |||::|||:||...||.||:||||||:.|.|...||||:
Human   335 HNAVSAYFAGNQKQLEQTLQQFNIKLRPPGAEKPSWLEE 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arfip	NP_650058.1	BAR_Arfaptin	140..338	CDD:153344	116/199 (58%)
ARFIP2	NP_001229783.1	BAR_Arfaptin	169..356	CDD:153344	106/186 (57%)