DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17187 and DNAJB14

DIOPT Version :9

Sequence 1:	NP_650056.1	Gene:	CG17187 / 41351	FlyBaseID:	FBgn0037882	Length:	299	Species:	Drosophila melanogaster
Sequence 2:	NP_001026893.1	Gene:	DNAJB14 / 79982	HGNCID:	25881	Length:	379	Species:	Homo sapiens

Alignment Length:	273	Identity:	56/273 - (20%)
Similarity:	107/273 - (39%)	Gaps:	81/273 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 NLYDLLGISLESDQNEIRKAYRKKALECHPDKNPDNPKAVERFHELSKALEILTDESARAAYDKV 74
            |.|::||::.::...:::|||||.||:.||||| ..|.|.:.|.::..|..:|::...|..||..
Human   108 NYYEVLGVTKDAGDEDLKKAYRKLALKFHPDKN-HAPGATDAFKKIGNAYAVLSNPEKRKQYDLT 171

  Fly    75 LKAKKA----------------AELRSRQL------------------DGK-----RQKLKLELE 100
            ...::|                |::....|                  :|:     :.:.:....
Human   172 GNEEQACNHQNNGRFNFHRGCEADITPEDLFNIFFGGGFPSGSVHSFSNGRAGYSQQHQHRHSGH 236

  Fly   101 ERER----------------------AALHKLAKSQ-PYSTVAKSDE-EVLHEQIERL------- 134
            |||.                      :.|.:|..|. |||...:|.. :.:..|.|.|
Human   237 EREEERGDGGFSVFIQLMPIIVLILVSLLSQLMVSNPPYSLYPRSGTGQTIKMQTENLGVVYYVN 301

  Fly   135 ----RREGSRLLEEEQRAMQEQF---RRNHAEQQKLQQQPVQFDSAQH---RIKMKWKAEPGQDY 189
                ......||::.:::::|.:   .||:..:::.|:..:|:.:..:   |::.|..|....:.
Human   302 KDFKNEYKGMLLQKVEKSVEEDYVTNIRNNCWKERQQKTDMQYAAKVYRDDRLRRKADALSMDNC 366

  Fly   190 TQQELLKYLKKYG 202
            .:.|.|..|.|.|
Human   367 KELERLTSLYKGG 379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17187	NP_650056.1	DnaJ	10..72	CDD:278647	22/61 (36%)
CG17187	NP_650056.1	RRM_DNAJC17	175..247	CDD:240875	8/31 (26%)
DNAJB14	NP_001026893.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	55..94
		DnaJ	107..>214	CDD:223560	27/106 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	219..241		4/21 (19%)
		DUF1977	271..371	CDD:370429	18/99 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910