DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17187 and Dnajc17

DIOPT Version :9

Sequence 1:	NP_650056.1	Gene:	CG17187 / 41351	FlyBaseID:	FBgn0037882	Length:	299	Species:	Drosophila melanogaster
Sequence 2:	NP_631878.2	Gene:	Dnajc17 / 69408	MGIID:	1916658	Length:	303	Species:	Mus musculus

Alignment Length:	311	Identity:	133/311 - (42%)
Similarity:	195/311 - (62%)	Gaps:	29/311 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SKKYSDVNLYDLLGISLESDQNEIRKAYRKKALECHPDKNPDNPKAVERFHELSKALEILTDESA 67
            :|:...::||.||||..::...|::||||:|||.||||||||||:|.|.||:||:|||:|||.:|
Mouse     4 TKELLQMDLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDNPRAAELFHQLSQALEVLTDAAA 68

  Fly    68 RAAYDKVLKAKKAAELRSRQLDGKRQKLKLELEERERAALHKLAKSQPYSTVAKSDEEVLHEQIE 132
            |||||||.||||.|..|:::||..|:|:||:||.|||.|....::.:..|..|.:    |.::|.
Mouse    69 RAAYDKVRKAKKQAAERTQRLDENRKKVKLDLEARERQAQAHGSEEEEESRSATT----LEQEIA 129

  Fly   133 RLRREGSRLLEEEQRAMQEQFRRNHAEQQKLQQQPVQFD-SAQHRIKMKWKAEPGQD----YTQQ 192
            |||.||||.|||:||.:|||.|::  .:|:|:.:....: ....::|:|||.:...:    |::.
Mouse   130 RLREEGSRQLEEQQRLIQEQIRQD--REQRLRGRTENTEGKGTPKLKLKWKCKKEDESQGGYSRD 192

  Fly   193 ELLKYLKKYGDVVALVVNSKRRGRAMVELATREACDMVLAYEKGDPAKPLHFEWVT--------- 248
            .||:.|:|||:|:.||::.|:.|.|:||.||..|.::.:..|.|....||...|:.
Mouse   193 VLLRLLQKYGEVLNLVLSRKKAGNAIVEFATVRAAELAVRNEVGLADNPLKVSWLEGQPQSTVDP 257

  Fly   249 -PPAADKQTTKSATTGCSASSTDYEDLVMRKLRQAEERKRLIEQMMKDEEG 298
             ||...|        |...|..|:|.|||.::|||.||::||.||.:::||
Mouse   258 GPPGLSK--------GSVLSERDFESLVMMRMRQAAERQQLIAQMQQEDEG 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17187	NP_650056.1	DnaJ	10..72	CDD:278647	40/61 (66%)
CG17187	NP_650056.1	RRM_DNAJC17	175..247	CDD:240875	26/75 (35%)
Dnajc17	NP_631878.2	DnaJ	11..73	CDD:278647	40/61 (66%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	104..123		5/18 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	150..170		3/21 (14%)
		RRM_DNAJC17	184..247	CDD:240875	22/62 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836925
Domainoid	1	1.000	94	1.000	Domainoid score	I7499
eggNOG	1	0.900	-	-		E1_COG2214
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H49527
Inparanoid	1	1.050	232	1.000	Inparanoid score	I3420
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55085
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005507
OrthoInspector	1	1.000	-	-		oto95252
orthoMCL	1	0.900	-	-		OOG6_103146
Panther	1	1.100	-	-	LDO	PTHR44313
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R269
SonicParanoid	1	1.000	-	-		X3927
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790