DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17187 and DNAJC17

DIOPT Version :9

Sequence 1:	NP_650056.1	Gene:	CG17187 / 41351	FlyBaseID:	FBgn0037882	Length:	299	Species:	Drosophila melanogaster
Sequence 2:	XP_016877890.1	Gene:	DNAJC17 / 55192	HGNCID:	25556	Length:	308	Species:	Homo sapiens

Alignment Length:	288	Identity:	129/288 - (44%)
Similarity:	186/288 - (64%)	Gaps:	26/288 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 EIRKAYRKKALECHPDKNPDNPKAVERFHELSKALEILTDESARAAYDKVLKAKKAAELRSRQLD 89
            :::||||:|||.||||||||||:|.|.||:||:|||:|||.:||||||||.||||.|..|:::||
Human    30 QVKKAYRQKALSCHPDKNPDNPRAAELFHQLSQALEVLTDAAARAAYDKVRKAKKQAAERTQKLD 94

  Fly    90 GKRQKLKLELEERERAALHKLAKSQPYSTVAKSDEEVLHEQIERLRREGSRLLEEEQRAMQEQFR 154
            .||:|:||:||.|||.|..:.::.:..|...::    |.::|||||.||||.|||:||.::||.|
Human    95 EKRKKVKLDLEARERQAQAQESEEEEESRSTRT----LEQEIERLREEGSRQLEEQQRLIREQIR 155

  Fly   155 -------RNHAEQQKLQQQPVQFDSAQHRIKMKWKAEPGQD----YTQQELLKYLKKYGDVVALV 208
                   |..||..:.|..|        ::|:|||.:...:    |::..||:.|:|||:|:.||
Human   156 QERDQRLRGKAENTEGQGTP--------KLKLKWKCKKEDESKGGYSKDVLLRLLQKYGEVLNLV 212

  Fly   209 VNSKRRGRAMVELATREACDMVLAYEKGDPAKPLHFEWV--TPPAADKQTTKSATTGCSASSTDY 271
            ::||:.|.|:||.||.:|.::.:..|.|....||...|:  .|..|..::....:.|...|..||
Human   213 LSSKKPGTAVVEFATVKAAELAVQNEVGLVDNPLKISWLEGQPQDAVGRSHSGLSKGSVLSERDY 277

  Fly   272 EDLVMRKLRQAEERKRLIEQM-MKDEEG 298
            |.|||.::|||.||::||.:| .:|:||
Human   278 ESLVMMRMRQAAERQQLIARMQQEDQEG 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17187	NP_650056.1	DnaJ	10..72	CDD:278647	33/46 (72%)
CG17187	NP_650056.1	RRM_DNAJC17	175..247	CDD:240875	27/75 (36%)
DNAJC17	XP_016877890.1	DnaJ	<30..77	CDD:278647	33/46 (72%)
DNAJC17	XP_016877890.1	RRM_DNAJC17	188..251	CDD:240875	23/62 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146980
Domainoid	1	1.000	94	1.000	Domainoid score	I7509
eggNOG	1	0.900	-	-		E1_COG2214
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H49527
Inparanoid	1	1.050	235	1.000	Inparanoid score	I3407
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55085
OrthoDB	1	1.010	-	-		D1405648at2759
OrthoFinder	1	1.000	-	-		FOG0005507
OrthoInspector	1	1.000	-	-		oto91671
orthoMCL	1	0.900	-	-		OOG6_103146
Panther	1	1.100	-	-	LDO	PTHR44313
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R269
SonicParanoid	1	1.000	-	-		X3927
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800