Protein Alignment CG17187 and DNAJC8

DIOPT Version :9

• Sequence 1: NP_650056.1
• Gene: CG17187 / 41351
• FlyBaseID: FBgn0037882
• Length: 299
• Species: Drosophila melanogaster
• Sequence 2: NP_055095.2
• Gene: DNAJC8 / 22826
• HGNCID: 15470
• Length: 253
• Species: Homo sapiens
• Alignment Length: 206
• Identity: 51/206 - (24%)
• Similarity: 95/206 - (46%)
• Gaps: 39/206 - (18%)

  Fly     6 YSDVNLYDLLGISLESDQNEIRKAYRKKALECHPDKNPDN-PKAVERFHELSKALEILTD-ESAR 68
            |.::|.:::|.|..|....||:|.:|:.::..|||||.|: .:|.:.|..:.||.::|.| |..:
Human    53 YFNLNPFEVLQIDPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKK 117

  Fly    69 AAYDKVLKAKKAAE----LRSRQL--DGK-----------------RQKLKL--ELE----ERER 104
            .|.|.:...|:..|    .|.:||  :||                 :|.:||  |||    |||.
Human   118 RALDVIQAGKEYVEHTVKERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAELEIKRKEREA 182

  Fly   105 AALHKLAKSQPYSTVAKSDEEVLHEQIERLRREGSRLLEEEQRAMQEQFRRNHAEQQKLQQQPVQ 169
            ..:|:..:.:        :||:..::..:..||..:..||.:....:.:|...|..:..:::..:
Human   183 KEMHERKRQR--------EEEIEAQEKAKREREWQKNFEESRDGRVDSWRNFQANTKGKKEKKNR 239

  Fly   170 FDSAQHRIKMK 180
            ......::||:
Human   240 TFLRPPKVKME 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17187	NP_650056.1	DnaJ	10..72	CDD:278647	22/63 (35%)
		RRM_DNAJC17	175..247	CDD:240875	2/6 (33%)
DNAJC8	NP_055095.2	CbpA	51..>238	CDD:225124	49/192 (26%)
		DnaJ	57..112	CDD:99751	19/54 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	181..253		12/78 (15%)
		Nuclear localization signal. /evidence=ECO:0000305|PubMed:27133716	189..192		0/2 (0%)
		Nuclear localization signal. /evidence=ECO:0000305|PubMed:27133716	203..206		0/2 (0%)
		Essential for polyglutamine aggregation suppression. /evidence=ECO:0000269|PubMed:27133716	232..253		2/19 (11%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910