DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17187 and dnj-27

DIOPT Version :9

Sequence 1:	NP_650056.1	Gene:	CG17187 / 41351	FlyBaseID:	FBgn0037882	Length:	299	Species:	Drosophila melanogaster
Sequence 2:	NP_001040704.1	Gene:	dnj-27 / 173065	WormBaseID:	WBGene00001045	Length:	788	Species:	Caenorhabditis elegans

Alignment Length:	401	Identity:	87/401 - (21%)
Similarity:	145/401 - (36%)	Gaps:	148/401 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 YDLLGISLESDQNEIRKAYRKKALECHPDKNPDNPKAVERFHELSKALEILTDESARAAYDKVLK 76
            |:|||:..::|...||||::|.|::.|||:|.|:|.|.:.|.:::||.|:|.||:.|..||:.
Worm    22 YELLGVERDADDRTIRKAFKKLAIKKHPDRNTDDPNAHDEFVKINKAYEVLKDENLRKKYDQF-- 84

  Fly    77 AKKAAELRSRQLDG-----KRQKLKL------------ELEERERAALHKLAKSQP-------YS 117
            .:|..|      ||     ..|..:.            |:....||...::.....       ||
Worm    85 GEKGLE------DGFQGGNNYQSWQFYNDNFGIYDDDQEIVTLNRADFQRMVSDSNEIWFINFYS 143

  Fly   118 TVAKSDEEV------LHEQIERLRREGSRLLEEEQRAMQEQ---------------FRRNHAEQQ 161
            |......::      ...:||...|.|:....|:.:..|.|               |.:.|.:.:
Worm   144 TYCSHCHQLAPTWRKFAREIEGTIRVGAVNCAEDPQLCQSQRVNAYPSLVFYPTGEFYQGHRDVE 208

  Fly   162 KLQQQPVQFDSAQHRIKMK--------WKA-----EP-----------GQDY-------TQQELL 195
                  :..|.|..|:|.:        |||     ||           |.|:       |:::|.
Worm   209 ------LMVDFAIQRLKSEVLHLNSENWKALSEDWEPYNRLPWVVDMCGGDHIDCLSSTTRRKLS 267

  Fly   196 KYLKKYGDVVALVVNSK-----------------------RRGRAMVE-LATREACDMVLAY--- 233
            ..|....:|..:..|::                       ::.:..:| :..:|....|:.|
Worm   268 SMLDGLANVATIDCNAEEALCSKFNPITSGVMWFPARKLVKKSQINIESMDAQEISKSVIQYLDE 332

  Fly   234 -------------EKGDPAKPLHFEWVTPPAADKQTTKS---------ATT-----GCSASSTDY 271
                         |..||.:|:.. |:.  |.|.|:|:.         .||     .||.||...
Worm   333 LEDISVESLQRLLEGNDPDEPIAV-WML--ANDAQSTERKDFRRLPALVTTQIFKFDCSKSSEIC 394

  Fly   272 EDLVMR-KLRQ 281
            ::|:.: ||.|
Worm   395 DELLDKTKLPQ 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17187	NP_650056.1	DnaJ	10..72	CDD:278647	26/59 (44%)
CG17187	NP_650056.1	RRM_DNAJC17	175..247	CDD:240875	22/142 (15%)
dnj-27	NP_001040704.1	DnaJ	18..>150	CDD:223560	39/135 (29%)
		DnaJ	20..82	CDD:278647	26/59 (44%)
		PDI_a_ERdj5_N	116..214	CDD:239301	16/103 (16%)
		Thioredoxin_like	222..>312	CDD:294274	12/89 (13%)
		ER_PDI_fam	438..750	CDD:273457
		PDI_a_ERdj5_C	438..543	CDD:239302
		PDI_a_ERdj5_C	549..664	CDD:239302
		PDI_a_ERdj5_C	670..773	CDD:239302
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910