DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17187 and AgaP_AGAP003825

DIOPT Version :9

Sequence 1:	NP_650056.1	Gene:	CG17187 / 41351	FlyBaseID:	FBgn0037882	Length:	299	Species:	Drosophila melanogaster
Sequence 2:	XP_310387.5	Gene:	AgaP_AGAP003825 / 1271565	VectorBaseID:	AGAP003825	Length:	308	Species:	Anopheles gambiae

Alignment Length:	306	Identity:	159/306 - (51%)
Similarity:	214/306 - (69%)	Gaps:	16/306 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 KKYSDVNLYDLLGISLESDQNEIRKAYRKKALECHPDKNPDNPKAVERFHELSKALEILTDESAR 68
            ||:||:::|.||.:.:.:.:.|||||||||||:||||||||||||.:.|.|||||||||.|.|||
Mosquito     5 KKFSDIDIYGLLEVDIAATEQEIRKAYRKKALQCHPDKNPDNPKAAQLFQELSKALEILMDVSAR 69

  Fly    69 AAYDKVLKAKKAAELRSRQLDGKRQKLKLELEERERAALHKLAKSQPYSTV-AKSDEEVLHEQIE 132
            ||||::|.|||||:||::|||.||||||.:||||||.|  |.|.|..|.|. :|:.||:..|:.:
Mosquito    70 AAYDRLLNAKKAAQLRTKQLDSKRQKLKADLEERERQA--KEAASGGYKTASSKTPEELFQEEFK 132

  Fly   133 RLRREGSRLLEEEQRAMQEQFRRNHAEQQKLQQQPV--QFDSAQHRIKMKWKAEPGQ----DYTQ 191
            |||:|||:|::|||..|:.|.:    |:.::.|...  .:|.||||||::|||:.|.    .||:
Mosquito   133 RLRKEGSKLIQEEQELMRRQLQ----EELRMMQTATAPSWDPAQHRIKIRWKADRGDAANGGYTE 193

  Fly   192 QELLKYLKKYGDVVALVVNSKRRGRAMVELATREACDMVLAYEKGDPAKPLHFEWVTPPAADKQT 256
            ..|.|:|.||||:.|||::.::.|.|:||...::|.:|.:.:|||....|...|||.......:.
Mosquito   194 DVLRKFLSKYGDLNALVMSPRKNGSALVEFRAKDAAEMAVTFEKGRLDNPCTLEWVGEAPTKGKA 258

  Fly   257 TKSATTGCSASSTDYEDLVMRKLRQAEERKRLIEQMMKDE---EGE 299
            ..:|:.|.:.:..|||.||:|:||||||||||||||||:|   |||
Mosquito   259 KATASGGSTITERDYESLVLRQLRQAEERKRLIEQMMKEEAEAEGE 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17187	NP_650056.1	DnaJ	10..72	CDD:278647	42/61 (69%)
CG17187	NP_650056.1	RRM_DNAJC17	175..247	CDD:240875	31/75 (41%)
AgaP_AGAP003825	XP_310387.5	DnaJ	11..73	CDD:278647	42/61 (69%)
AgaP_AGAP003825	XP_310387.5	RRM_DNAJC17	173..249	CDD:240875	31/75 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	102	1.000	Domainoid score	I13088
eggNOG	1	0.900	-	-		E1_COG2214
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H49527
Inparanoid	1	1.050	295	1.000	Inparanoid score	I5140
OMA	1	1.010	-	-		QHG55085
OrthoDB	1	1.010	-	-		D1405648at2759
OrthoFinder	1	1.000	-	-		FOG0005507
OrthoInspector	1	1.000	-	-		oto111324
Panther	1	1.100	-	-	LDO	PTHR44313
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3927
TreeFam	1	0.960	-	-
	13	12.940