Protein Alignment GCC88 and ATGRIP

DIOPT Version :10

• Sequence 1: NP_650055.1
• Gene: GCC88 / 41350
• FlyBaseID: FBgn0037881
• Length: 695
• Species: Drosophila melanogaster
• Sequence 2: NP_851277.1
• Gene: ATGRIP / 836733
• AraportID: AT5G66030
• Length: 788
• Species: Arabidopsis thaliana
• Alignment Length: 826
• Identity: 176/826 - (21%)
• Similarity: 335/826 - (40%)
• Gaps: 213/826 - (25%)

  Fly     6 RELEALVSTQKEQLGRYEKRLKD------------VVTAYKGLLKEKEALETSLAAHAEATAVGE 58
            :|.:.:...::..:.:.:|.|.|            ::.....|..|.:.|.:......:..|.|.
plant     5 KESDVVGEEEESHVIKEDKELNDASNETLTENGDQLLQMIAELRLENDFLRSQFEGLKDEVAQGR 69

  Fly    59 SGSPARELESKKTSTDSADGATEGAAPGPPAPPAEGQLQTQIITLMNSL-----ATLSAEKS--- 115
            |...|.::|:     |||.               ..|||.|:.:|...:     ..::||::
plant    70 SLQKAEQVEA-----DSAQ---------------LKQLQEQVASLSREIDVEKQTRVAAEQALEH 114

  Fly   116 RMEASFQADKK--QLRSQIAQKEQTI-QELNTRAKEQA----------ARAKSDVDEIKAKWIVE 167
            ..||..:||.|  :..|:.:|.||.: ||:..|.::.|          .|||..:.||
plant   115 LREAYSEADAKSQEYSSKFSQVEQKLDQEIKERDEKYADLDAKFTRLHKRAKQRIQEI------- 172

  Fly   168 RQEREKETNNQMLMIRELQKLYADERHLKDNIEMQLNNFKTQFASNE------AENSRLR----E 222
                :||.::.....||:.:  ..||....:..||....:|:..:||      ||..:||    :
plant   173 ----QKEKDDLDARFREVNE--TAERASSQHSSMQQELERTRQQANEALKAMDAERQQLRSANNK 231

  Fly   223 LQSQLKEARSQLKQFQAKTEHSAAASASADSAALLQQVRLEMQQLKEQHAVAIRQ----EQRRVL 283
            |:..::|.|..|:..:.|.|  ....:..|...:|:.::.::|.::|:..:|:.:    .|:.:.
plant   232 LRDTIEELRGSLQPKENKIE--TLQQSLLDKDQILEDLKKQLQAVEERKQIAVTELSAKHQKNLE 294

  Fly   284 RAEEQ-----SRRQAALHEDRVASLEARLAELSTTV--------GSYDRLRQQDQDSIHDLKQQL 335
            ..|.|     |.|..|  .:.::||:..|||..:.:        |...|||.    :...||.:|
plant   295 GLEAQVVDALSERDKA--AETISSLQVLLAEKESKIAEMEAAATGEAARLRA----AAETLKGEL 353

  Fly   336 QDLEQAHVR----------------PTSNSRALNEDVDVA----TLVDEMVRLKKLLTTANARSA 380
            ..|:..:.:                ..:.|..|..:::||    .|..||....::|:|.:|...
plant   354 AHLKSENEKEKETWEASCDALKSKLEIAESNYLQAEIEVAKMRSQLGSEMSMQTQILSTKDAELK 418

  Fly   381 NPLDLGEILSFSGQ-TATRVESHAHCEQQLQGVQQMLEASKQQRQL--LEQKVQLQHSHI----- 437
            ...:  ||.....: ::.::.:||    .||.....|.|:|...|:  ||:.::.....:
plant   419 GARE--EINRLQSEFSSYKIRAHA----LLQKKDMELAAAKDSEQIKSLEEALKEAEKEVYLVSA 477

  Fly   438 ------QTLQEKVQVLNRNIDEAEVELKQQGEKLR-LALK---------NERTKWQEAKAELENE 486
                  |.||..:..|.:.::|....||...|::: |.:|         .|:..|:|....|| |
plant   478 ERDRAQQDLQSALASLEKELEERAGALKDASEQIKSLEVKLDSTVARNQAEKQAWEEDLRVLE-E 541

  Fly   487 T---RCKL--------------NELE--QLLQKQ--------RQRSLQLLDEKEQEIK------- 517
            |   ||:.              .|||  :|..|:        |:.:.:|::||::||.
plant   542 TWRRRCEALTAQNEASPAEGIEKELENAKLRNKRMKEEHESVRELADRLIEEKDREISRLVDEMT 606

  Fly   518 TLQTSFEVFHSASGVGSTLATPTLEAAADSFHYSSDTDSVEGEQRERKLKVRSKKMSMGENCHML 582
            .|:.|.|            :.|....:....|:..: ::.|.:|::    |.:...|..|: .:|
plant   607 NLRKSME------------SKPVWNKSPSQVHHYGN-NNTESQQQD----VSNLSTSAAEH-QIL 653

  Fly   583 HYANELARKDIEITTLRKAKYAAESTLRK-AIQDKVTSQQEMHEKIECLKEQVDRLERCKTREGA 646
            ..|.:.|:::.|:...::...|.:..:.: ..::::.||||     ..||.::..:||.:.|||.
plant   654 ILARQQAQREEELAQTQRHILALQEEIEELERENRLHSQQE-----AVLKTELREMERKQKREGV 713

  Fly   647 NLEYLKNVIISYIVTRDADGKRHMLNAISAVLQFTAAEMQAINASF 692
            ::.||||||:..:.|.:.:.   :|..:..:|||:..|:|....::
plant   714 DMTYLKNVILKLLETGEVEA---LLPVVGMLLQFSPEEIQKCQQAY 756

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GCC88	NP_650055.1	Smc	<33..>341	CDD:440809	81/355 (23%)
		SMC_prok_B	219..>527	CDD:274008	87/406 (21%)
		GRIP	645..688	CDD:460221	14/42 (33%)
ATGRIP	NP_851277.1	Smc	<3..614	CDD:440809	140/668 (21%)
		Grip	712..755	CDD:197860	14/45 (31%)