Protein Alignment GCC88 and Golgin97

DIOPT Version :10

• Sequence 1: NP_650055.1
• Gene: GCC88 / 41350
• FlyBaseID: FBgn0037881
• Length: 695
• Species: Drosophila melanogaster
• Sequence 2: NP_610875.1
• Gene: Golgin97 / 36492
• FlyBaseID: FBgn0086757
• Length: 611
• Species: Drosophila melanogaster
• Alignment Length: 730
• Identity: 147/730 - (20%)
• Similarity: 283/730 - (38%)
• Gaps: 207/730 - (28%)

  Fly    38 KEKEALETSLAAHAEATAVGESGSPARELESKKTS--TDSADGATEGAAPGPPAPPAE-----GQ 95
            |.||.....:...|.....|.:.:..| |.|::.|  ::|||....|..........|     .:
  Fly     8 KIKEETGDDVVQSANQRYPGNNNNNYR-LRSRRVSINSNSADDVGGGGFYNESEQLCELRSQCNE 71

  Fly    96 LQTQIITLMNSLATLSAEKSRMEASFQADKKQLRSQIAQKE---------QTIQ--ELNTRAKEQ 149
            |.|::.|:...|..|..||:|::.:.:...:.:|....||:         |.:|  |::......
  Fly    72 LTTKLSTVTQGLQQLQEEKTRVDKTNEILLESVRVAQTQKDIYCEEQEKIQNLQQIEIDKLKNLL 136

  Fly   150 AARAKSDVDEIKAKWIVERQEREKET-NNQMLMIRELQKLYADER----HLKDNIEMQLNNFKTQ 209
            :.|.:..||.:   .::.:|.::.|: :.::..:|.::.:..|.|    .|:.:.:.:.|...|.
  Fly   137 SFREQESVDRM---GLMRQQTQQIESLSEELERLRPIESVAEDLRDELEQLRHSTQQEKNLLTTT 198

  Fly   210 FASNEAENSRLRELQSQLKEARSQLKQFQAKTEHSAAASASADSAALLQQVRLEMQQLKEQHA-- 272
            .|:.:.||..|::....::|:|         .|.....::.....||:::.:|..|.|:|.|.
  Fly   199 LAAVQEENRHLKKRMKIVEESR---------LESLGKLNSEQQVQALIREHKLLEQHLEEAHLQL 254

  Fly   273 -----------VAIRQEQRRVLR--AEEQSRRQAAL--HEDRVASLEARLAELSTTVGSYDRLRQ 322
                       :|:..:..|:.:  |||.:.::.||  .:|.:.|.:....||..   :.|.::|
  Fly   255 SDIKGSWSGQNLALETQVSRLSKQVAEETTEKRKALKSRDDAIESRKQVSFELEK---AKDEIKQ 316

  Fly   323 QDQDSIHDLKQQLQDLEQA--HVRPTSNSRALNEDVDVATLVDEMVRLKKLLTTANARSANPLDL 385
            :| |.:..|::::.:|..|  ..|..:..:.|.|......|..|:..||..||.|:.|      .
  Fly   317 RD-DKVKLLEEEIDELSVALKECREENEQQVLFERNKSQNLETEVKDLKTRLTAADDR------F 374

  Fly   386 GEILSFSGQTATRVESH-AHCEQQLQGVQQMLEASKQQR--------------QLLEQKVQLQHS 435
            .|..|.:.|.|.::... ...::||......||..::::              .:|.|:::|:.|
  Fly   375 SEYSSNAEQVAQKLRVQVTEKQEQLDETIMQLEIEREEKMTAILRNAEIAQSEDILRQQLRLERS 439

  Fly   436 HIQTLQEKVQVLNRNIDEAEVELKQ-------QGEKLRLALKNERTKWQEAKAEL--ENETRCKL 491
            ....|||:...|.|:|.||...|:|       ..:||        |:::..:.|:  :|:|...|
  Fly   440 EASDLQERNNQLVRDISEARQTLQQVSSTAQDNADKL--------TEFERVQLEIIEKNKTIKTL 496

  Fly   492 N----ELEQLLQKQRQRSLQLLDEKEQEIKTLQTSFEVFHSASGVGSTLATPTLEAAADSFHYSS 552
            |    :|::.:||: .||.|:..:.|.            |..:..|..:::.:|||
  Fly   497 NQRLIDLKKTVQKE-LRSAQISTDSES------------HPTTTPGHRISSSSLEA--------- 539

  Fly   553 DTDSVEGEQRERKLKVRSKKMSMGE--NCHMLHYANELARKDIEITTLRKAKYAAESTLRKAIQD 615
                                .|.|:  ||                                .|.|
  Fly   540 --------------------FSTGDKGNC--------------------------------VIMD 552

  Fly   616 KVTSQQEMHEKIECLKEQVDRLERCKTREGANLEYLKNVIISYIVTRDADGKRHMLNAISAVLQF 680
            :|                             |.:|||:||:.::.:|:.:. ||::.|:|.:||.
  Fly   553 EV-----------------------------NFQYLKHVIVKFLTSREVEA-RHLVRAVSTLLQL 587

  Fly   681 TAAEMQAINASFQKK 695
            |..|.:.::.:...|
  Fly   588 TTEEEKLLHDTLNWK 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GCC88	NP_650055.1	Smc	<33..>341	CDD:440809	70/342 (20%)
		SMC_prok_B	219..>527	CDD:274008	77/354 (22%)
		GRIP	645..688	CDD:460221	15/42 (36%)
Golgin97	NP_610875.1	SMC_prok_B	<71..465	CDD:274008	89/415 (21%)
		Grip	553..598	CDD:197860	16/74 (22%)