Protein Alignment GCC88 and GCC88

DIOPT Version :10

• Sequence 1: NP_650055.1
• Gene: GCC88 / 41350
• FlyBaseID: FBgn0037881
• Length: 695
• Species: Drosophila melanogaster
• Sequence 2: XP_313518.5
• Gene: GCC88 / 1274400
• VectorBaseID: AGAMI1_003174
• Length: 661
• Species: Anopheles gambiae
• Alignment Length: 719
• Identity: 228/719 - (31%)
• Similarity: 393/719 - (54%)
• Gaps: 92/719 - (12%)

  Fly     1 MEKRQ------RELEALVSTQKEQLGRYEKRLKDVVTAYKGLLKEKEALETSLAA---------- 49
            |||::      :|.|:::|:|||.:.|||.||||::.||||::|||.|||.:|.|
Mosquito     1 MEKKRHESNKLKEYESIISSQKEHINRYENRLKDIIVAYKGIVKEKAALEETLKALQKVNDGKEA 65

  Fly    50 ------HAEATAVGESGSPARELESKKTSTDSADGATEGAAPGPPAPPAEGQLQTQIITLMNSLA 108
                  |..:.||..|||                              .|||||    ||||:|.
Mosquito    66 ILANGLHECSEAVLASGS------------------------------VEGQLQ----TLMNNLT 96

  Fly   109 TLSAEKSRMEASFQADKKQLRSQIAQKEQTIQELNTRAKEQAARAKSDVDEIKAKWIVERQEREK 173
            |::||::|:|...:.::.|||.::|.|:..|:||:.|.|:..::::.::........|:...|..
Mosquito    97 TITAERNRIEEVSKYERNQLRQKLANKDSIIEELSRRIKDFESQSQFEMSSFNPNTPVDYGPRMG 161

  Fly   174 ETNNQMLMIRELQKLYADERHLKDNIEMQLNNFKTQFASNEAENSRLRELQSQLKEARSQLKQFQ 238
            .:.:|.:.||||:||..|||:|.:.:|:||.|.||||.....:...:.      |:.....|...
Mosquito   162 PSEDQSVKIRELKKLLDDERNLNEQLELQLGNLKTQFMVIAPDRHTVS------KKLVDPKKTTP 220

  Fly   239 AKTEHSAAASASADSAALLQQVRLEMQQLKEQHAVAIRQEQRRVLRAEEQSRRQAALHEDRVASL 303
            ...:.....::|.:....|::::.||..||:|:|:|:.:|::||..|||.|:|...:||:|||:.
Mosquito   221 TDCDSKGTNNSSINLKESLRELQDEMNHLKKQYAIAVAEEKQRVRLAEENSKRLREIHEERVANF 285

  Fly   304 EARLAELSTTVGSYDRLRQQDQDSIHDLKQQLQDLEQAHVRPTSNSRALNEDVDVATLVDEMVRL 368
            |:|:.|||..||.|||:::||:..|..||..:.:|:...|...::|...:.:     .:::....
Mosquito   286 ESRIKELSEMVGRYDRIKEQDKVYILQLKTAIANLKTKRVEENNDSPQYDRE-----SIEDGYGA 345

  Fly   369 KKLLTTANARSANPLDLGEILSFSGQTATRVESHAHCEQQLQGVQQMLEASKQQRQLLEQKVQLQ 433
            .:|| ..|..:....:..|.|||..:.|.. :.||....:|:..::..|.:..:.|.|::.:.|.
Mosquito   346 GQLL-VENHSTGGITERKEDLSFLAEIAPE-DQHADETNELKMYKRRYEQAMDENQRLKRDLLLC 408

  Fly   434 HSHIQTLQEKVQVLNRNIDEAEVELKQQGEKLRLALKNERTKWQEAKAELENETRCKLNELEQLL 498
            ..::..|::|:.:..::..:.|.:|||:....::|||||..|..||...|:.....|:..|:..|
Mosquito   409 QENVSQLKQKIGIQKQSTAQIEFDLKQKITDQQIALKNESVKHTEALIALQASFERKITHLQDSL 473

  Fly   499 QKQRQRSLQLLDEKEQEIKTLQTSFEVFHSASGVGSTLATPTLEAAADSFHYSSDTDSVEGEQRE 563
            |.||:|||.::||||:|||||:||.|:...:|.           :|...||    .|::.....:
Mosquito   474 QNQRERSLAVMDEKEEEIKTLRTSLEILSLSSA-----------SATQEFH----NDAIGNRLVD 523

  Fly   564 RK--------LKVRSKKMSMGENCHMLHYANELARKDIEITTLRKAKYAAESTLRKAIQDKVTSQ 620
            |.        :.|.|.:....::.|::|||.|:||.::||:.||.:|.::|::|||..|:|:..:
Mosquito   524 RSDSNSEPSFMMVTSLQSLSEDHQHLIHYAQEIARMNVEISALRTSKNSSEASLRKLAQEKLMIE 588

  Fly   621 QEMHEKIECLKEQVDRLERCKTREGANLEYLKNVIISYIVTRDADGKRHMLNAISAVLQFTAAEM 685
            :....:|..::::::||.|.:..||:||||||||::|:::::|.:.|:||.|||:|||:|...|:
Mosquito   589 ETYKTQISAMEKEMERLRRNRQLEGSNLEYLKNVVLSFLLSKDTECKKHMTNAIAAVLKFDENEV 653

  Fly   686 QAIN 689
            :|:|
Mosquito   654 KAVN 657

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GCC88	NP_650055.1	Smc	<33..>341	CDD:440809	103/323 (32%)
		SMC_prok_B	219..>527	CDD:274008	93/307 (30%)
		GRIP	645..688	CDD:460221	22/42 (52%)
GCC88	XP_313518.5	None