DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment scpr-C and CRISPLD2

DIOPT Version :9

Sequence 1:	NP_001287282.1	Gene:	scpr-C / 41348	FlyBaseID:	FBgn0037879	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_113664.1	Gene:	CRISPLD2 / 83716	HGNCID:	25248	Length:	497	Species:	Homo sapiens

Alignment Length:	220	Identity:	57/220 - (25%)
Similarity:	78/220 - (35%)	Gaps:	50/220 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 REVKIEPHHKLILNLFNELRNNVAGGKIEGLPKAVRMAKMSWCEELSHLALLNVKTC--ESLPDK 111
            ||.|.|     ||.|.|:||..|.       |:|..|..|:|.:||...|......|  |..|
Human    53 REDKEE-----ILMLHNKLRGQVQ-------PQASNMEYMTWDDELEKSAAAWASQCIWEHGP-- 103

  Fly   112 CRSTERFAYAGQNNAVFQYSGAE-TEYTDAEIIKEQIENWFAE--------RSNASPEILASFPE 167
               |......|||      .||. ..|.....   .:::|:.|        .|..:|..    ||
Human   104 ---TSLLVSIGQN------LGAHWGRYRSPGF---HVQSWYDEVKDYTYPYPSECNPWC----PE 152

  Fly   168 ELPNKAVTKFTIAVAEKNTHVGCAA------VRFSRDFYNHFVLTCNFA-TSNIVGQPVYTPGEK 225
            .......|.:|..|......:|||.      ..:...:.|.....||:: ..|.:|:..|..| :
Human   153 RCSGPMCTHYTQIVWATTNKIGCAVNTCRKMTVWGEVWENAVYFVCNYSPKGNWIGEAPYKNG-R 216

  Fly   226 ATTGCKNRYGAAYDYPNLCYAKEIY 250
            ..:.|...||.:. ..||||.:|.|
Human   217 PCSECPPSYGGSC-RNNLCYREETY 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scpr-C	NP_001287282.1	SCP_euk	58..210	CDD:240180	40/168 (24%)
CRISPLD2	NP_113664.1	SCP_euk	56..201	CDD:240180	42/174 (24%)
		LCCL	286..370	CDD:128866
		LCCL	387..479	CDD:128866
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151216
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.850