DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RpL3 and rpl3

DIOPT Version :9

Sequence 1:	NP_524316.1	Gene:	RpL3 / 41347	FlyBaseID:	FBgn0020910	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_001001590.1	Gene:	rpl3 / 322571	ZFINID:	ZDB-GENE-030131-1291	Length:	403	Species:	Danio rerio

Alignment Length:	403	Identity:	297/403 - (73%)
Similarity:	348/403 - (86%)	Gaps:	1/403 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSHRKFSAPRHGSMAFYPKKRSARHRGKVKAFPKDDASKPVHLTCFIGYKAGMTHIVREADRPGS 65
            |||||||||.|||:.|.|:||..|||||||:|||||.|||||||.|:||||||||||||.|||||
Zfish     1 MSHRKFSAPLHGSLGFLPRKRCKRHRGKVKSFPKDDPSKPVHLTAFLGYKAGMTHIVREVDRPGS 65

  Fly    66 KINKKEVVEAVTVLETPPMIVVGAVGYIETPFGLRALVNVWAQHLSEECRRRFYKNWYKSKKKAF 130
            |:|||||||||||:|||||||||.|||:.||.|||:...::|:|:|:||:|||||||||||||||
Zfish    66 KVNKKEVVEAVTVVETPPMIVVGVVGYVMTPRGLRSFKTIFAEHISDECKRRFYKNWYKSKKKAF 130

  Fly   131 TKASKKWTDDLGKKSIENDFRKMLRYCKVIRVIAHSQIRLIKQRQKKAHVMEIQLNGGSIEDKVK 195
            ||..|:|.|:.|||.:|.||..|.:||::||:|||:|:||:..||||:|:||||||||:|.|||.
Zfish   131 TKYCKRWQDEEGKKQLEKDFSSMKKYCQIIRIIAHTQMRLLPHRQKKSHLMEIQLNGGTISDKVD 195

  Fly   196 WAREHLEKPIQVSNVFGQDEMIDCVGVTKGKGFKGVTSRWHTKKLPRKTHKGLRKVACIGAWHPS 260
            ||||.||:.|.::|||.||||||.:|||||.|.|||||||||||||||||:|||||||||||||:
Zfish   196 WAREKLEQSIPIANVFSQDEMIDVIGVTKGHGCKGVTSRWHTKKLPRKTHRGLRKVACIGAWHPA 260

  Fly   261 RVSTTVARAGQKGYHHRTEINKKIYRIGAGIHTKDGKVIKNNASTEYDLTDKSITPMGGFPHYGE 325
            ||:.:||||||||||||||||||||:||.|.|.||||::||||||:|||::|||.|:|||.||||
Zfish   261 RVAFSVARAGQKGYHHRTEINKKIYKIGVGYHNKDGKLVKNNASTDYDLSNKSINPLGGFVHYGE 325

  Fly   326 VNNDFVMIKGCCIGSKKRIITLRKSLLKHTKRSALEQIKLKFIDTSSKMGHGRFQTPADKLAFMG 390
            |.|||:|:|||.:|:|||::|||||||..|.|.|.|:|.||||||:||.|||||||..:|..|||
Zfish   326 VTNDFLMLKGCVVGTKKRVLTLRKSLLVQTSRRAQEKIDLKFIDTTSKFGHGRFQTIEEKKTFMG 390

  Fly   391 PLKKDRL-KEEAA 402
            ||||||| |||.|
Zfish   391 PLKKDRLAKEEMA 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpL3	NP_524316.1	PTZ00103	1..400	CDD:240267	294/399 (74%)
rpl3	NP_001001590.1	PTZ00103	1..400	CDD:240267	293/398 (74%)
rpl3	NP_001001590.1	RplC	3..375	CDD:294230	273/371 (74%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587212
Domainoid	1	1.000	599	1.000	Domainoid score	I190
eggNOG	1	0.900	-	-		E1_COG0087
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H747
Inparanoid	1	1.050	638	1.000	Inparanoid score	I800
OMA	1	1.010	-	-		QHG62184
OrthoDB	1	1.010	-	-		D362198at33208
OrthoFinder	1	1.000	-	-		FOG0001847
OrthoInspector	1	1.000	-	-		oto41384
orthoMCL	1	0.900	-	-		OOG6_100665
Panther	1	1.100	-	-	LDO	PTHR11363
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1136
SonicParanoid	1	1.000	-	-		X1206
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800