DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RpL3 and rpl301

DIOPT Version :9

Sequence 1:	NP_524316.1	Gene:	RpL3 / 41347	FlyBaseID:	FBgn0020910	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_593471.1	Gene:	rpl301 / 2542265	PomBaseID:	SPAC17A5.03	Length:	388	Species:	Schizosaccharomyces pombe

Alignment Length:	395	Identity:	258/395 - (65%)
Similarity:	315/395 - (79%)	Gaps:	9/395 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSHRKFSAPRHGSMAFYPKKRSARHRGKVKAFPKDDASKPVHLTCFIGYKAGMTHIVREADRPGS 65
            |||.||..|||||:.|.|:||::|.|||||||||||||||||||.|:|||||||||||:.|||||
pombe     1 MSHCKFEQPRHGSLGFLPRKRASRQRGKVKAFPKDDASKPVHLTAFLGYKAGMTHIVRDLDRPGS 65

  Fly    66 KINKKEVVEAVTVLETPPMIVVGAVGYIETPFGLRALVNVWAQHLSEECRRRFYKNWYKSKKKAF 130
            |::|:|::|||||:|||||:|||.|||:|||.|||:|..|||:|||||.:|||||||:|||||||
pombe    66 KMHKREILEAVTVIETPPMVVVGVVGYVETPRGLRSLTTVWAEHLSEEVKRRFYKNWFKSKKKAF 130

  Fly   131 TKASKKWTDDLGKKSIENDFRKMLRYCKVIRVIAHSQIRLIKQRQKKAHVMEIQLNGGSIEDKVK 195
            ||.:||:.:  ..:||..:..::.:||.|:||:||:|||.....|||||:||||:||||:.|||:
pombe   131 TKYAKKYAE--STQSINRELERIKKYCSVVRVLAHTQIRKTPLAQKKAHLMEIQVNGGSVADKVE 193

  Fly   196 WAREHLEKPIQVSNVFGQDEMIDCVGVTKGKGFKGVTSRWHTKKLPRKTHKGLRKVACIGAWHPS 260
            |||||.||.:.:.:.|.|:||||.:|||:|||.:|.|:||.||:||||||:|||||||||||||:
pombe   194 WAREHFEKTVDIKSTFEQNEMIDVIGVTRGKGNEGTTARWGTKRLPRKTHRGLRKVACIGAWHPA 258

  Fly   261 RVSTTVARAGQKGYHHRTEINKKIYRIGAGIHTKDGKVIKNNASTEYDLTDKSITPMGGFPHYGE 325
            .|..||||||..||.|||::|.||||||||...|       ||||::|.|:|.|||||||..||.
pombe   259 NVQWTVARAGNAGYMHRTQLNSKIYRIGAGDDAK-------NASTDFDATEKRITPMGGFVRYGV 316

  Fly   326 VNNDFVMIKGCCIGSKKRIITLRKSLLKHTKRSALEQIKLKFIDTSSKMGHGRFQTPADKLAFMG 390
            |.|||||:.|...|..||::|||||||.||.|.|||.:.||:|||:||.|||||||||:...|:|
pombe   317 VENDFVMLNGATPGPVKRVLTLRKSLLTHTSRKALEPVSLKWIDTASKFGHGRFQTPAEAKQFLG 381

  Fly   391 PLKKD 395
            .||||
pombe   382 TLKKD 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpL3	NP_524316.1	PTZ00103	1..400	CDD:240267	258/395 (65%)
rpl301	NP_593471.1	PTZ00103	1..388	CDD:240267	258/395 (65%)
rpl301	NP_593471.1	RplC	3..366	CDD:294230	241/371 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	515	1.000	Domainoid score	I49
eggNOG	1	0.900	-	-		E1_COG0087
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H747
Inparanoid	1	1.050	544	1.000	Inparanoid score	I204
OMA	1	1.010	-	-		QHG62184
OrthoFinder	1	1.000	-	-		FOG0001847
OrthoInspector	1	1.000	-	-		otm47303
orthoMCL	1	0.900	-	-		OOG6_100665
Panther	1	1.100	-	-	LDO	PTHR11363
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1136
SonicParanoid	1	1.000	-	-		X1206
TreeFam	1	0.960	-	-
	14	13.860