Protein Alignment CG6689 and Zfp974

DIOPT Version :10

• Sequence 1: NP_650051.1
• Gene: CG6689 / 41345
• FlyBaseID: FBgn0037877
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: NP_001360956.1
• Gene: Zfp974 / 73430
• MGIID: 1920680
• Length: 826
• Species: Mus musculus
• Alignment Length: 237
• Identity: 66/237 - (27%)
• Similarity: 115/237 - (48%)
• Gaps: 26/237 - (10%)

  Fly   367 KEERNLIRRAQLRAKPPNFVCDQCGQAFRMSHNLRIHMLRHTRTKNYQCTECPKTFYDAYMRNMH 431
            |..::|::..::.:....|.|.:||:||.:..:|..|...||..|:::|.||.|.|..|.....|
Mouse   425 KRNKSLMQHQKIHSGERPFQCQECGKAFIVLAHLTRHQTIHTGEKSFECKECGKKFRTATHLVQH 489

  Fly   432 IRIRHRGETPFACGFCSETFAYPGARQKHESEVHNAAPRLIVKRINPKPMPKPRESVRYQCKLCQ 496
            ..| |.||.||.|..|.:.|.......:|: :.|                   .|:..::|.:|.
Mouse   490 QSI-HTGEKPFECNVCGKAFRLQIYLSEHQ-KTH-------------------MEAKHFECNICG 533

  Fly   497 KHYASKYALGWHIKSHTDANAYKCQRCSKSYSDPNKLKRHEMTH-EKRPLQCDVCLKGFYQRTRL 560
            |.:..:..|..|.|:||:...:||:.|..::....:|.:|...| :::|.||..|.|.|.||:..
Mouse   534 KVFRLQVYLSEHQKTHTEEKPFKCKLCGSAFRSKYQLSKHHTVHTDEKPYQCKECGKCFRQRSNF 598

  Fly   561 REHELIHTGERPYWCEVCNVNFRYK----YNMKSHANSKMHQ 598
            .:|:.||||::|:.|:.|...:|..    .:.|||::.:.::
Mouse   599 TDHQSIHTGKKPFQCKECGKFYRLNTLLIRHQKSHSSERPYE 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6689	NP_650051.1	THAP	2..94	CDD:214951
		zf-AD	166..241	CDD:462262
		zf-C2H2	385..407	CDD:395048	8/21 (38%)
		C2H2 Zn finger	387..407	CDD:275368	7/19 (37%)
		C2H2 Zn finger	415..436	CDD:275368	8/20 (40%)
		C2H2 Zn finger	444..460	CDD:275368	3/15 (20%)
		C2H2 Zn finger	492..512	CDD:275368	6/19 (32%)
		C2H2 Zn finger	520..540	CDD:275368	4/19 (21%)
		C2H2 Zn finger	547..567	CDD:275368	7/19 (37%)
		zf-met	573..597	CDD:463736	6/27 (22%)
		C2H2 Zn finger	575..591	CDD:275368	4/19 (21%)
Zfp974	NP_001360956.1	KRAB	14..75	CDD:214630
		C2H2 Zn finger	175..195	CDD:275368
		COG5048	199..574	CDD:227381	44/169 (26%)
		C2H2 Zn finger	203..223	CDD:275368
		C2H2 Zn finger	231..251	CDD:275368
		C2H2 Zn finger	277..297	CDD:275368
		C2H2 Zn finger	305..325	CDD:275368
		C2H2 Zn finger	333..353	CDD:275368
		C2H2 Zn finger	361..381	CDD:275368
		C2H2 Zn finger	389..409	CDD:275368
		COG5048	411..781	CDD:227381	66/237 (28%)
		C2H2 Zn finger	417..437	CDD:275368	2/11 (18%)
		C2H2 Zn finger	445..465	CDD:275368	7/19 (37%)
		C2H2 Zn finger	473..493	CDD:275368	8/20 (40%)
		C2H2 Zn finger	501..521	CDD:275368	4/20 (20%)
		C2H2 Zn finger	529..549	CDD:275368	6/19 (32%)
		C2H2 Zn finger	557..577	CDD:275368	4/19 (21%)
		C2H2 Zn finger	585..605	CDD:275368	7/19 (37%)
		C2H2 Zn finger	613..633	CDD:275368	4/19 (21%)
		C2H2 Zn finger	641..661	CDD:275368	66/237 (28%)
		C2H2 Zn finger	669..689	CDD:275368
		C2H2 Zn finger	697..717	CDD:275368
		C2H2 Zn finger	725..745	CDD:275368
		C2H2 Zn finger	753..773	CDD:275368
		C2H2 Zn finger	781..801	CDD:275368