DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6689 and CG4936

DIOPT Version :9

Sequence 1:NP_650051.1 Gene:CG6689 / 41345 FlyBaseID:FBgn0037877 Length:613 Species:Drosophila melanogaster
Sequence 2:NP_650862.1 Gene:CG4936 / 42393 FlyBaseID:FBgn0038768 Length:521 Species:Drosophila melanogaster


Alignment Length:529 Identity:120/529 - (22%)
Similarity:181/529 - (34%) Gaps:165/529 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   167 CRTCYNDFTADFRAKDLFDPANSVLLFHIEVISGVWI---SHKPDEPRLMCPACKSALDQAIDFR 228
            ||.|... ..:..|....|.:...|...|....||.|   .|.||:   :|..|...|..|..||
  Fly    23 CRVCLQQ-PKEPMASIFNDDSEKDLTHMIRECGGVPIKQFDHYPDK---ICEKCFKVLKMAFKFR 83

  Fly   229 EMC-------------ISTELKLSQAK---------PSTDEVQIEAENENPISSD---------- 261
            |.|             :..|.:..:.|         |..|..:.|.|.|:....:          
  Fly    84 ETCQRSYGHLRQFVGPVEVEQRPPEKKGSETATKLEPDVDPDEAEQEPEHDEEDEDVDLDESHYA 148

  Fly   262 -------------HDLISD-------------TENTNVEE------------------IEDAGGD 282
                         ||.|.|             .:|..|||                  |.|.|.|
  Fly   149 EADDAAETQGGVFHDEIEDGILVELEKDRIVHVKNEQVEEDGIIEEVYDVYETYEGDLIPDQGYD 213

  Fly   283 H-VEDEATSDDQTSQEAVDEV-----AESPAAQDPLSVALGAKIFKELLDQYTGKEKARLRKGAP 341
            | :.|:|.|:.....|.:|:|     .|| |.:|...|.|.:     ..:::...:..|    |.
  Fly   214 HEMADQALSELSAEIEYLDQVEHDQLTES-AHEDDAEVDLNS-----TEEEFVPSKSVR----AS 268

  Fly   342 IASKPKAKEKAAGEQKPKRSA-----------NPKTKEERNLIRRAQLRAKPPNFVCDQCGQAFR 395
            |.::...|.:.    .|:|||           ..||.:..|     .|:.:..|  .|..|....
  Fly   269 IHARNATKRRV----NPRRSATSTASVAVESSTSKTTDRGN-----PLKVRRGN--SDSAGSKMS 322

  Fly   396 MSHNLRIHM-----LRHTRTKNYQCTECPKTFYDAYMRNMH-IRIRHRGETPFACGFCSETFAYP 454
            :.....|.:     .:|:..|.               :..| |.:..:.|..:.|..|..  .||
  Fly   323 IKSEKDISIGEVLARKHSGIKT---------------KGGHKILLGDKKEFKYICDVCGN--MYP 370

  Fly   455 G-ARQKHESEVHNAAPRLIVKRINPKPMPKPRESVRYQCKLCQKHYASKYALGWHIKSHTDANAY 518
            . :|.....:||:..              ||.|     |::|...:|....|..|:.:||....|
  Fly   371 SQSRLTEHIKVHSGV--------------KPHE-----CEICGHCFAQAQQLARHMNTHTGNRPY 416

  Fly   519 KCQRCSKSYSDPNKLKRHEMTH-EKRPLQCDVCLKGFYQRTRLREHELIHTGERPYWCEVCNVNF 582
            ||..|..:::|.:...:|...| .:||.:||||.|.|.....|:.|::|||||:|:.|:||...|
  Fly   417 KCSYCPAAFADLSTRNKHHRIHTNERPYECDVCHKTFTYTNTLKFHKMIHTGEKPHVCDVCGKGF 481

  Fly   583 RYKYNMKSH 591
            ...|.:::|
  Fly   482 PQAYKLRNH 490

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6689NP_650051.1 THAP 2..96 CDD:283206
zf-AD 167..240 CDD:214871 22/88 (25%)
zf-C2H2 385..407 CDD:278523 3/26 (12%)
C2H2 Zn finger 387..407 CDD:275368 3/24 (13%)
zf-H2C2_2 399..422 CDD:290200 3/27 (11%)
C2H2 Zn finger 415..436 CDD:275368 2/21 (10%)
C2H2 Zn finger 444..460 CDD:275368 5/16 (31%)
C2H2 Zn finger 492..512 CDD:275368 5/19 (26%)
C2H2 Zn finger 520..540 CDD:275368 4/19 (21%)
C2H2 Zn finger 547..567 CDD:275368 8/19 (42%)
zf-met 574..597 CDD:289631 6/18 (33%)
C2H2 Zn finger 575..591 CDD:275368 5/15 (33%)
CG4936NP_650862.1 zf-AD 22..95 CDD:214871 21/75 (28%)
C2H2 Zn finger 362..382 CDD:275368 5/21 (24%)
zf-H2C2_2 375..399 CDD:290200 7/42 (17%)
COG5048 386..>447 CDD:227381 19/65 (29%)
C2H2 Zn finger 390..410 CDD:275368 5/19 (26%)
zf-H2C2_2 403..426 CDD:290200 8/22 (36%)
C2H2 Zn finger 418..438 CDD:275368 4/19 (21%)
zf-H2C2_2 432..455 CDD:290200 10/22 (45%)
C2H2 Zn finger 446..466 CDD:275368 8/19 (42%)
zf-H2C2_2 459..481 CDD:290200 11/21 (52%)
C2H2 Zn finger 474..494 CDD:275368 6/17 (35%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45449441
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.840

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