DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6689 and CG1663

DIOPT Version :9

Sequence 1:	NP_650051.1	Gene:	CG6689 / 41345	FlyBaseID:	FBgn0037877	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_610521.1	Gene:	CG1663 / 36012	FlyBaseID:	FBgn0033449	Length:	387	Species:	Drosophila melanogaster

Alignment Length:	378	Identity:	83/378 - (21%)
Similarity:	126/378 - (33%)	Gaps:	71/378 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   246 DEVQIEAEN--ENPISSDHDLISDTEN-TNVEEIEDAGGDHV--EDEATSDDQTSQEAVDEVAES 305
            ||||:|..|  ...|:.:..|....|: .|||.:|:....:.  |.|...|:..|....|.::..
  Fly    23 DEVQVEMTNLLAASIAQESKLAEVQESFKNVEFMEEEVEPNFSPEKEQGHDELASNSHHDYISNQ 87

  Fly   306 PAAQDPLSVALGAKIFKELLDQYTGK-----EKARLRKGAPIASKPKAKEKAAGEQKPKRSANPK 365
            |           .|.|..|.....|.     ::.|..|...|......|       |.:..::.|
  Fly    88 P-----------HKAFYSLQRTSPGVIQYFIQQLRRHKFFWITEHGINK-------KDRMDSSQK 134

  Fly   366 TKEERNLIRRAQLRAKPP---------------NFVCDQCGQAFRMSHNLRIHMLRHTRTKNY-- 413
            ..|.  |..|...:..|.               .:|.......||..:....|.|......|:
  Fly   135 VAEA--LFHRFHFQLDPKVVNASARFLQVWFERQYVMQLSSSDFRCRYPKYYHSLLKFMPTNHIS 197

  Fly   414 --QCTECPKTFYDAYMRNMHIRIRHRGETPFACGFCSETFAYPGARQKHESEVHNAAPRLIVKRI 476
              .|.||.:.|.:..:..:|....|.|..|..|..|.::|......::|::..|...|
  Fly   198 VTICEECDRRFLNERLLRLHKFRVHGGPNPNVCHVCHQSFPLASKLEQHQARYHFKRP------- 255

  Fly   477 NPKPMPKPRESVRYQCKLCQKHYASKYALGWHIKSHTDANAYKCQRCSKSYSDPNKLKRHEMTHE 541
                        .:||..|..:..||:....|...|.....|.|:.|..|....:.|..|..||:
  Fly   256 ------------EWQCSRCDYNAPSKWDFQQHQAMHAGQRNYICELCGHSSKTSSALAVHRRTHD 308

  Fly   542 KRPLQCDVCLKGFYQRTRLREH-ELIHTGE--RPYWCEVCNVNFRYKYNMKSH 591
            :..|.|..|.:.|.:.:.|:.| ..||.|.  |...|:.|...|:....:|.|
  Fly   309 QPKLCCPHCSRQFRENSTLKSHIRKIHDGNSARQVSCDFCWRRFKTLELLKLH 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6689	NP_650051.1	THAP	2..96	CDD:283206
		zf-AD	167..240	CDD:214871
		zf-C2H2	385..407	CDD:278523	5/21 (24%)
		C2H2 Zn finger	387..407	CDD:275368	4/19 (21%)
		zf-H2C2_2	399..422	CDD:290200	6/26 (23%)
		C2H2 Zn finger	415..436	CDD:275368	5/20 (25%)
		C2H2 Zn finger	444..460	CDD:275368	3/15 (20%)
		C2H2 Zn finger	492..512	CDD:275368	5/19 (26%)
		C2H2 Zn finger	520..540	CDD:275368	5/19 (26%)
		C2H2 Zn finger	547..567	CDD:275368	5/20 (25%)
		zf-met	574..597	CDD:289631	5/18 (28%)
		C2H2 Zn finger	575..591	CDD:275368	4/15 (27%)
CG1663	NP_610521.1	MttA_Hcf106	<33..>91	CDD:294511	13/68 (19%)
		C2H2 Zn finger	201..222	CDD:275368	5/20 (25%)
		C2H2 Zn finger	259..279	CDD:275368	5/19 (26%)
		C2H2 Zn finger	287..307	CDD:275368	5/19 (26%)
		C2H2 Zn finger	314..335	CDD:275368	5/20 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3304
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.950