DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6689 and Zfp629

DIOPT Version :9

Sequence 1:	NP_650051.1	Gene:	CG6689 / 41345	FlyBaseID:	FBgn0037877	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	XP_006508015.1	Gene:	Zfp629 / 320683	MGIID:	2444524	Length:	976	Species:	Mus musculus

Alignment Length:	439	Identity:	104/439 - (23%)
Similarity:	158/439 - (35%)	Gaps:	128/439 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   263 DLISDTENTNVEEIEDAGGDHVEDEATSDDQTSQEAV-DEVAESPAAQDPLSVALGA-------- 318
            ||....|:.|  |.....|...|:|:...:.:.:|.: .:.|:||.::||..:.|.:
Mouse   120 DLQGPEESQN--EAHRGAGSGNEEESPQQESSGEEIILGDPAQSPESKDPSEMPLESPSQDASAP 182

  Fly   319 -----KIFKELLDQYTGKEKARLR------------------------KGAPI--ASKPKAKE-- 350
                 .:....||..|..:.:...                        ...|:  ||:|..:|
Mouse   183 QDSPTPLGSSPLDHQTPMDPSAPEVVPSPSEWTKACETNWQWGTLTPWNSTPVVTASEPSLRELV 247

  Fly   351 --KAAGEQKP----------------------KRSANPKTKEE--------RNLIRRAQLRAKPP 383
              :.:|.:||                      .....|.|..|        .:|::..:......
Mouse   248 QGRPSGAEKPYICNECGKSFSQWSKLLRHQRIHTGERPNTCSECGKSFTQSSHLVQHQRTHTGEK 312

  Fly   384 NFVCDQCGQAFRMSHNLRIHMLRHTRTKNYQCTECPKTFYDAYMRNMHIRIRHRGETPFACGFCS 448
            .:.|..||:.|..|.||..|...||..|.|:||||.|.|..:.....|.| .|.||.|:.||.|.
Mouse   313 PYKCPDCGKCFSWSSNLVQHQRTHTGEKPYKCTECEKAFTQSTNLIKHQR-SHTGEKPYKCGECR 376

  Fly   449 ETFAYPGARQKHESEVHNAAPRLIVKRINPKPMPKPRESVRYQCKLCQKHYASKYALGWHIKSHT 513
            ..|.......:|:: .|..              .||     |:|..|.|.:...:.|..|.|.|.
Mouse   377 RAFYRSSDLIQHQA-THTG--------------EKP-----YKCPECGKRFGQNHNLLKHQKIHA 421

  Fly   514 DANAYKCQRCSKSYSDPNKLKRHEMTHE-KRPLQCDVCLKGF--------YQRTRLRE------- 562
            ....|:|..|.||:...::|.:|:.||. ::|.:|..|.|.|        :|||.|||
Mouse   422 GEKPYRCTECGKSFIQSSELTQHQRTHTGEKPYECLECGKSFGHSSTLIKHQRTHLREDPFKCPV 486

  Fly   563 -------------HELIHTGERPYWCEVCNVNFRYKYNMKSHANSKMHQ 598
                         |:..|||||||.|..|..:|....|:.:|  .::|:
Mouse   487 CGKTFTLSATLLRHQRTHTGERPYKCPECGKSFSVSSNLINH--QRIHR 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6689	NP_650051.1	THAP	2..96	CDD:283206
		zf-AD	167..240	CDD:214871
		zf-C2H2	385..407	CDD:278523	8/21 (38%)
		C2H2 Zn finger	387..407	CDD:275368	8/19 (42%)
		zf-H2C2_2	399..422	CDD:290200	12/22 (55%)
		C2H2 Zn finger	415..436	CDD:275368	8/20 (40%)
		C2H2 Zn finger	444..460	CDD:275368	4/15 (27%)
		C2H2 Zn finger	492..512	CDD:275368	6/19 (32%)
		C2H2 Zn finger	520..540	CDD:275368	6/19 (32%)
		C2H2 Zn finger	547..567	CDD:275368	11/47 (23%)
		zf-met	574..597	CDD:289631	5/22 (23%)
		C2H2 Zn finger	575..591	CDD:275368	4/15 (27%)
Zfp629	XP_006508015.1	PHA03169	<118..>269	CDD:223003	26/150 (17%)
		COG5048	251..629	CDD:227381	81/306 (26%)
		C2H2 Zn finger	260..280	CDD:275368	0/19 (0%)
		C2H2 Zn finger	288..308	CDD:275368	2/19 (11%)
		C2H2 Zn finger	316..336	CDD:275368	8/19 (42%)
		C2H2 Zn finger	344..364	CDD:275368	8/20 (40%)
		C2H2 Zn finger	372..392	CDD:275368	5/20 (25%)
		C2H2 Zn finger	400..420	CDD:275368	6/19 (32%)
		C2H2 Zn finger	428..448	CDD:275368	6/19 (32%)
		C2H2 Zn finger	456..476	CDD:275368	6/19 (32%)
		C2H2 Zn finger	484..504	CDD:275368	1/19 (5%)
		C2H2 Zn finger	512..532	CDD:275368	5/21 (24%)
		C2H2 Zn finger	540..560	CDD:275368
		C2H2 Zn finger	568..588	CDD:275368
		C2H2 Zn finger	596..616	CDD:275368
		C2H2 Zn finger	624..644	CDD:275368
		C2H2 Zn finger	679..699	CDD:275368
		C2H2 Zn finger	772..792	CDD:275368
		C2H2 Zn finger	824..844	CDD:275368
		C2H2 Zn finger	877..897	CDD:275368
		C2H2 Zn finger	951..971	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24376
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100