Protein Alignment CG6689 and LOC1277133

DIOPT Version :10

• Sequence 1: NP_650051.1
• Gene: CG6689 / 41345
• FlyBaseID: FBgn0037877
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: XP_316572.5
• Gene: LOC1277133 / 1277133
• VectorBaseID: AGAMI1_000147
• Length: 778
• Species: Anopheles gambiae
• Alignment Length: 678
• Identity: 132/678 - (19%)
• Similarity: 227/678 - (33%)
• Gaps: 223/678 - (32%)

  Fly    35 PDTFKAW------LAFCGYTEESLKLKNPCICIEHFKDEDIEGSLKFEMGLAKKRTLRPGAVPCV 93
            ||..:|.      :..|.:||:         |..|   ..:.|          .|.|...|:|.|
Mosquito    68 PDAMRALVDGRSKVCSCHFTED---------CFGH---HPVYG----------YRYLLATALPTV 110

  Fly    94 NKSQESGSDRARKERSQRRRNQELVAELLAEEEAKLIHPEATSFEQDS------VYLSET----- 147
            ..        .|||..|.:                   |::...|:|.      |||.:.
Mosquito   111 FP--------PRKEIEQPK-------------------PDSAELEKDPALDYFLVYLDDPPGPAF 148

  Fly   148 --------VTMELDPLSGEEKLE---ELQKCRTCYNDFTADFRAKDLFDPANSVLLFH------- 194
                    ||..||.:.....||   |.::.....:|       .:|.:.:|.|:...
Mosquito   149 IDQVALAGVTSGLDVIGNNTPLEVKPEQEQAAIQEDD-------AELQEESNDVVTIEDEDGEDD 206

  Fly   195 -------IEVISGVWISHKPDEPRLMCPACKSALDQAIDFREMCISTELKLSQAKPSTDEVQIEA 252
                   ||..:|.:...|.|             |:.....::.:|.|      :|:.:|::..
Mosquito   207 DAIEQIGIEYANGKYYFLKLD-------------DEPAPVGDVLVSAE------EPNGNELEFR- 251

  Fly   253 ENENPISSD-------HDLISDTENTNVEEIEDAGGDHVEDEATSDDQTSQEAVDEVAESPAAQD 310
            .:||..|:|       |||     |.|:::::.........||...|:...:..|:..|..|
Mosquito   252 NSENATSTDADQEKSLHDL-----NENLQQLDKFVSQQDVGEADEYDEYEMDVSDQETEQFA--- 308

  Fly   311 PLSVALGAKIFKELLDQYTGKEKARLRKGAPI----------ASKPKAKEKAAG--------EQK 357
                  |.::..|.:::.:..:...::....:          :||..|.:...|        :..
Mosquito   309 ------GKQVHLETVEERSDTDVIEVKDDTEVDVVKEEYEVTSSKDTASDSETGGDDNDYDCDAL 367

  Fly   358 PKRSANPKTKEERNLIRRAQLRAKPPN-----FVCDQCGQAFRMSHNLRIHMLRHTRTKNYQCTE 417
            .:....|....|...:...::|.:..|     |.|:.||:.||.......|.|.||:.|.:.|..
Mosquito   368 SEADYGPIEALEEVSVCGDKVRIRDENEGLNRFFCEYCGRGFRFKSLKDRHTLVHTKMKKFCCEV 432

  Fly   418 CPKTFYDAYMRNMHIRIRHRGET---PFACGFCSETFAYPGARQKHESEVHNAAPRLIVKRINPK 479
            |.:.|.......:|:| .|.||:   .|.|..|.:.     ..:..|.|.|..|        :.:
Mosquito   433 CGRGFTQKINLTIHLR-THTGESGNKKFTCQICGKK-----CIRMSELEAHMTA--------HLR 483

  Fly   480 PMPKPRESVRYQCKLCQKHYASKYALGWHIK-SH------------------------------- 512
            ..|       :.|.|||:.|:....|..|.: .|
Mosquito   484 KFP-------HVCPLCQERYSDATGLYDHFQVEHRSEMTLRELIDLLSENENAIVISDKEAPSNI 541

  Fly   513 -TDANAYKCQRCSKSYSDPNKLKRHEMTHEKRPLQCDVCLKGFYQRTRLREHELIHTGERPYWCE 576
             .|..:|:|..|||:|.....|:||:.....:...|..|.:.|..::.|.:|...||.|:||.|.
Mosquito   542 RRDDGSYECPVCSKTYRMEANLERHKRKMHVKIYNCPHCPRKFLYKSLLHKHLPSHTLEKPYQCP 606

  Fly   577 VCNVNFRYKYNMKSHANSKMHQDNARKL 604
            .|.:::..:.|::.|    |.:.:|::|
Mosquito   607 HCALSYTQRVNLRVH----MERKHAQQL 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6689	NP_650051.1	THAP	2..94	CDD:214951	13/64 (20%)
		zf-AD	166..241	CDD:462262	12/88 (14%)
		zf-C2H2	385..407	CDD:395048	8/21 (38%)
		C2H2 Zn finger	387..407	CDD:275368	7/19 (37%)
		C2H2 Zn finger	415..436	CDD:275368	5/20 (25%)
		C2H2 Zn finger	444..460	CDD:275368	2/15 (13%)
		C2H2 Zn finger	492..512	CDD:275368	7/20 (35%)
		C2H2 Zn finger	520..540	CDD:275368	8/19 (42%)
		C2H2 Zn finger	547..567	CDD:275368	5/19 (26%)
		zf-met	573..597	CDD:463736	5/23 (22%)
		C2H2 Zn finger	575..591	CDD:275368	3/15 (20%)
LOC1277133	XP_316572.5	None