DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG6689 and LOC11175757

DIOPT Version :10

Sequence 1:NP_650051.1 Gene:CG6689 / 41345 FlyBaseID:FBgn0037877 Length:613 Species:Drosophila melanogaster
Sequence 2:XP_061497423.1 Gene:LOC11175757 / 11175757 VectorBaseID:AGAMI1_005304 Length:595 Species:Anopheles gambiae


Alignment Length:456 Identity:91/456 - (19%)
Similarity:152/456 - (33%) Gaps:180/456 - (39%)


- Green bases have known domain annotations that are detailed below.


  Fly    27 GFFRFPKCPDTFKAWLAFCGYTEESLKLKN------------PCICIEHF-----KDEDIEGSLK 74
            |...||:.|.:|...:        .|.|||            ..:| |||     .....:.||:
Mosquito   214 GVKTFPRPPYSFSCLI--------GLALKNSHSGLLPVPDIYSFVC-EHFPYFRTAPRGWKNSLR 269

  Fly    75 FEMGLAKKRTLRPGAVPC---VNKSQESGS-----------DRARK--ERSQR--RRNQELVAEL 121
            ..:.|:|          |   :.|...||:           |:..|  |..||  ||:.:::.:.
Mosquito   270 HNLSLSK----------CFKKIEKPLSSGAYRKCFFWMIKPDKQAKLDEAVQRWFRRDPDIIRQA 324

  Fly   122 LAEEEAKLIHPE-ATSFEQDSV----YLSETVTME--LDPLSGEEKLEELQKCRTCYNDFTADF- 178
            :|       ||| .|:.|:..:    .|.:.:.:|  ||..:|||             |...:| 
Mosquito   325 MA-------HPEYLTALERGEMKHGSVLYDHIDLEDDLDEDNGEE-------------DDDVEFI 369

  Fly   179 --RAKDLFDPANSVLLFHIEVISGVWISHKPDEPRLMCPACKSALDQAIDFREM-CISTE----L 236
              ..:.|.|.|...::..::  :|:    |.|:.           |...:..|| ..|||    :
Mosquito   370 EPEGETLDDDAERYIIATLD--AGL----KDDDE-----------DDDDNEEEMPTWSTENRQTI 417

  Fly   237 KLSQAKP------STDEVQIEAENENP------ISSDHDLI---SDTENTNVEEI-----EDAGG 281
            :|...:|      ..:|..:|.|.|..      |...|:.|   :|.....:.|:     |:.||
Mosquito   418 QLPMIEPGQIVANEVEEEYLELEEEGDDDGMEIIEPKHETIDFDADRSIIKMPELVIHGEEEEGG 482

  Fly   282 DHVE---------DEATSDDQTSQEAVDEVAESPAAQDPLSVALGAKIFKELLDQYTGKEKARLR 337
            ..|.         ..|..|.:.|..|:.|:.|    :|.:|:        |..|::..|:     
Mosquito   483 HQVNFNLEVPDYYASAKVDSKHSMLALAELTE----EDLVSL--------ENEDEFLLKQ----- 530

  Fly   338 KGAPIASKPKAKEKAAGEQKPKRSANPKT---------------------KEERNLIRRAQLRAK 381
                   ..|.:::...:...||.:|..:                     |..|.|.:|:..|..
Mosquito   531 -------PQKHRQQTEQQNSAKRVSNDTSETGVSFQQHFEQLQKQQYRLRKHSRQLRQRSARRKV 588

  Fly   382 P 382
            |
Mosquito   589 P 589

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6689NP_650051.1 THAP 2..94 CDD:214951 18/86 (21%)
zf-AD 166..241 CDD:462262 15/82 (18%)
zf-C2H2 385..407 CDD:395048
C2H2 Zn finger 387..407 CDD:275368
C2H2 Zn finger 415..436 CDD:275368
C2H2 Zn finger 444..460 CDD:275368
C2H2 Zn finger 492..512 CDD:275368
C2H2 Zn finger 520..540 CDD:275368
C2H2 Zn finger 547..567 CDD:275368
zf-met 573..597 CDD:463736
C2H2 Zn finger 575..591 CDD:275368
LOC11175757XP_061497423.1 None
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.