Protein Alignment CG6689 and ZNF197

DIOPT Version :9

• Sequence 1: NP_650051.1
• Gene: CG6689 / 41345
• FlyBaseID: FBgn0037877
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: NP_001310222.1
• Gene: ZNF197 / 10168
• HGNCID: 12988
• Length: 1029
• Species: Homo sapiens
• Alignment Length: 233
• Identity: 78/233 - (33%)
• Similarity: 113/233 - (48%)
• Gaps: 28/233 - (12%)

  Fly   370 RNLIRRAQLRAKPPNFVCDQCGQAFRMSHNLRIHMLRHTRTKNYQCTECPKTFYDAYMRNM--HI 432
            ||||...::.:....:.||:||:.|.:..:|..|...|||.|:|:|.:|.|.|  :|..|:  |.
Human   775 RNLIEHKRIHSGEKPYECDECGKCFILKKSLIGHQRIHTREKSYKCNDCGKVF--SYRSNLIAHQ 837

  Fly   433 RIRHRGETPFACGFCSETFAYPGARQKHESEVHNAAPRLIVKRINPKPMPKPRESVRYQCKLCQK 497
            || |.||.|:||..|.:.|.|.....:|: .:|:.                   ...|:|.:|:|
Human   838 RI-HTGEKPYACSECGKGFTYNRNLIEHQ-RIHSG-------------------EKTYECHVCRK 881

  Fly   498 HYASKYALGWHIKSHTDANAYKCQRCSKSYSDPNKLKRHEMTHE-KRPLQCDVCLKGFYQRTRLR 561
            ...|...|..|.:.||....|||..|.|.:|....|..|:..|. ::|.:||.|.|.|..:..|.
Human   882 VLTSSRNLMVHQRIHTGEKPYKCNECGKDFSQNKNLVVHQRMHTGEKPYECDKCRKSFTSKRNLV 946

  Fly   562 EHELIHTGERPYWCEVCNVNFRYKYNMKSHANSKMHQD 599
            .|:.|||||:||.|..|:..||.:.|:..|  .|:|.|
Human   947 GHQRIHTGEKPYGCNDCSKVFRQRKNLTVH--QKIHTD 982

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6689	NP_650051.1	THAP	2..96	CDD:283206
		zf-AD	167..240	CDD:214871
		zf-C2H2	385..407	CDD:278523	7/21 (33%)
		C2H2 Zn finger	387..407	CDD:275368	7/19 (37%)
		zf-H2C2_2	399..422	CDD:290200	10/22 (45%)
		C2H2 Zn finger	415..436	CDD:275368	9/22 (41%)
		C2H2 Zn finger	444..460	CDD:275368	4/15 (27%)
		C2H2 Zn finger	492..512	CDD:275368	6/19 (32%)
		C2H2 Zn finger	520..540	CDD:275368	6/19 (32%)
		C2H2 Zn finger	547..567	CDD:275368	7/19 (37%)
		zf-met	574..597	CDD:289631	7/22 (32%)
		C2H2 Zn finger	575..591	CDD:275368	5/15 (33%)
ZNF197	NP_001310222.1	SCAN	38..150	CDD:128708
		KRAB	216..256	CDD:307490
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	262..290
		C2H2 Zn finger	372..392	CDD:275368
		zf-H2C2_2	384..409	CDD:316026
		C2H2 Zn finger	400..420	CDD:275368
		COG5048	424..853	CDD:227381	32/80 (40%)
		C2H2 Zn finger	428..448	CDD:275368
		C2H2 Zn finger	456..476	CDD:275368
		C2H2 Zn finger	484..504	CDD:275368
		C2H2 Zn finger	512..532	CDD:275368
		C2H2 Zn finger	540..560	CDD:275368
		C2H2 Zn finger	568..588	CDD:275368
		C2H2 Zn finger	596..616	CDD:275368
		C2H2 Zn finger	624..644	CDD:275368
		C2H2 Zn finger	652..672	CDD:275368
		C2H2 Zn finger	680..700	CDD:275368
		C2H2 Zn finger	708..728	CDD:275368
		C2H2 Zn finger	736..756	CDD:275368
		COG5048	760..>1026	CDD:227381	78/233 (33%)
		C2H2 Zn finger	764..784	CDD:275368	4/8 (50%)
		C2H2 Zn finger	792..812	CDD:275368	7/19 (37%)
		C2H2 Zn finger	820..840	CDD:275368	9/22 (41%)
		C2H2 Zn finger	848..868	CDD:275368	5/20 (25%)
		C2H2 Zn finger	876..896	CDD:275368	6/19 (32%)
		C2H2 Zn finger	904..924	CDD:275368	6/19 (32%)
		C2H2 Zn finger	932..952	CDD:275368	7/19 (37%)
		C2H2 Zn finger	960..980	CDD:275368	7/21 (33%)
		C2H2 Zn finger	988..1008	CDD:275368

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24376
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.100