Protein Alignment CG6689 and znf347

DIOPT Version :10

• Sequence 1: NP_650051.1
• Gene: CG6689 / 41345
• FlyBaseID: FBgn0037877
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: XP_031753259.1
• Gene: znf347 / 100379887
• XenbaseID: XB-GENE-6039618
• Length: 1199
• Species: Xenopus tropicalis
• Alignment Length: 598
• Identity: 142/598 - (23%)
• Similarity: 221/598 - (36%)
• Gaps: 125/598 - (20%)

  Fly    65 KDED-IEGSLKFEMGLAKKRTLRP-GAVPCVNKSQESGSDRARKERSQRRRNQE----LVAELLA 123
            ||.| :|.:....|.........| |||.|     .|..||...:.||.....|    ...|.:.
 Frog   264 KDSDALEPAASLAMDCTNNLPFCPEGAVTC-----SSQLDRGEGQLSQPLGTAEGKGVAFTEGVD 323

  Fly   124 EEEAKLIHPEA------TSFEQDSVYLSE-TVTMELDPLSGEEKLEELQKCRTCYNDFTADFRAK 181
            :...|.:.|..      |..|.:.|:.|: |:...|....|:... ....|..|:...|:
 Frog   324 KMRVKFLDPAPKAERPHTCAECNKVFYSKRTLKAHLRAHLGDRSY-ICNVCGKCFRRHTS----- 382

  Fly   182 DLFDPANSVLLFHIEVISGVWISHKPDEPRLMCPACKSALDQAIDFREMCISTELKLSQAKPSTD 246
                     ||.|..:.:|        |....||.|..:..|         ...|...| |..|.
 Frog   383 ---------LLIHERIHTG--------ERPYQCPQCGKSFVQ---------RQHLNTHQ-KTHTG 420

  Fly   247 EVQIEAEN-------ENPISSDHDLISDTENTNVEEIEDAGGDHVEDEATSDDQTSQEAVDEVAE 304
            |...:...       .:.::..|       ..:.||:.|         :::.|:..:..:.|.:.
 Frog   421 ERPFQCAECGKGFRWRSELAKHH-------KVHEEEVAD---------SSAKDERGESDIGEKSG 469

  Fly   305 SPAAQDPLSVALGAKIFKELLDQYTGKEKARLRKGAPIASK-PKAKEKAAGEQKPKRSANPKTKE 368
            |..:      |.||...|.:.|....:..|...:||....: |::.:..|..:..|...|.:|.:
 Frog   470 SSVS------AGGANAGKRVTDSQNKRGGAARPRGAHTHPRNPRSDKAHACAECGKVFYNKRTLK 528

  Fly   369 ERNLIRRAQLRAKPPNFVCDQCGQAFRMSHNLRIHMLRHTRTKNYQCTECPKTFYDAYMRNMHIR 433
            ..   .||.|..:  :::|:.||:.||....|.||...||..:.|:|.:|.|.|........|:|
 Frog   529 SH---LRAHLGER--SYICNVCGKCFRRHTALLIHERIHTGERPYKCIQCGKRFVQQQHLTTHLR 588

  Fly   434 IRHRGETPFACGFCSETFAYPGARQKHESEVH---------------NAAPRLIVKRIN------ 477
             .|.|..||.|..|..::.:.....||: :||               :|..|..::|::
 Frog   589 -THTGIKPFPCDVCGNSYRWRSELAKHQ-KVHEEENSGNGSEDGQKESAIKRRCLRRVDRGTLGT 651

  Fly   478 ---PKPMPK----------PRESVRYQCKLCQKHYASKYALGWHIKSHTDANAYKCQRCSKSYSD 529
               .|.:.|          .:....:.|..|.|::.:|..|..|.:.|||..:|.|..|.||:..
 Frog   652 LERGKALGKRARLLLRQRAQKAERTHSCPECGKNFINKRTLRSHQRVHTDERSYICNVCGKSFRR 716

  Fly   530 PNKLKRHEMTHE-KRPLQCDVCLKGFYQRTRLREHELIHTGERPYWCEVCNVNFRYKYNMKSHAN 593
            ...|..||..|. :||.||..|.|.|.||..|..|...||||:|:.|..|...||::..:..|
 Frog   717 HTSLLIHERIHTGERPYQCAQCGKSFVQRQHLTTHLKTHTGEKPFQCAQCGKGFRWRSELAKH-- 779

  Fly   594 SKMHQDNARKLGV 606
            .|:|:|.:..:||
 Frog   780 QKVHEDESLLVGV 792

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6689	NP_650051.1	THAP	2..94	CDD:214951	10/30 (33%)
		zf-AD	166..241	CDD:462262	13/74 (18%)
		zf-C2H2	385..407	CDD:395048	8/21 (38%)
		C2H2 Zn finger	387..407	CDD:275368	8/19 (42%)
		C2H2 Zn finger	415..436	CDD:275368	6/20 (30%)
		C2H2 Zn finger	444..460	CDD:275368	2/15 (13%)
		C2H2 Zn finger	492..512	CDD:275368	6/19 (32%)
		C2H2 Zn finger	520..540	CDD:275368	7/19 (37%)
		C2H2 Zn finger	547..567	CDD:275368	8/19 (42%)
		zf-met	573..597	CDD:463736	6/23 (26%)
		C2H2 Zn finger	575..591	CDD:275368	4/15 (27%)
znf347	XP_031753259.1	C2H2 Zn finger	103..123	CDD:275368
		C2H2 Zn finger	131..151	CDD:275368
		zf-H2C2_2	143..168	CDD:463886
		zf-C2H2	157..179	CDD:395048
		C2H2 Zn finger	159..179	CDD:275368
		zf-H2C2_2	171..194	CDD:463886
		C2H2 Zn finger	187..207	CDD:275368
		KRAB_A-box	213..252	CDD:143639
		PHA00733	<335..386	CDD:177301	12/65 (18%)
		C2H2 Zn finger	342..362	CDD:275368	5/19 (26%)
		C2H2 Zn finger	370..390	CDD:275368	6/33 (18%)
		COG5048	394..915	CDD:227381	108/440 (25%)
		C2H2 Zn finger	398..418	CDD:275368	7/29 (24%)
		C2H2 Zn finger	426..446	CDD:275368	1/26 (4%)
		C2H2 Zn finger	514..534	CDD:275368	4/22 (18%)
		C2H2 Zn finger	542..562	CDD:275368	8/19 (42%)
		C2H2 Zn finger	570..590	CDD:275368	6/20 (30%)
		C2H2 Zn finger	598..618	CDD:275368	4/20 (20%)
		C2H2 Zn finger	655..671	CDD:275368	2/15 (13%)
		C2H2 Zn finger	679..699	CDD:275368	6/19 (32%)
		C2H2 Zn finger	707..727	CDD:275368	7/19 (37%)
		C2H2 Zn finger	735..755	CDD:275368	8/19 (42%)
		C2H2 Zn finger	763..783	CDD:275368	6/21 (29%)
		C2H2 Zn finger	838..858	CDD:275368
		COG5048	865..1186	CDD:227381
		C2H2 Zn finger	869..889	CDD:275368
		C2H2 Zn finger	897..917	CDD:275368
		C2H2 Zn finger	925..945	CDD:275368
		KRAB_A-box	951..989	CDD:143639
		C2H2 Zn finger	1081..1101	CDD:275368
		C2H2 Zn finger	1110..1130	CDD:275368
		C2H2 Zn finger	1138..1158	CDD:275368
		C2H2 Zn finger	1166..1186	CDD:275368