DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4820 and wdn

DIOPT Version :9

Sequence 1:	NP_001097748.1	Gene:	CG4820 / 41344	FlyBaseID:	FBgn0037876	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	NP_476900.1	Gene:	wdn / 43398	FlyBaseID:	FBgn0005642	Length:	869	Species:	Drosophila melanogaster

Alignment Length:	298	Identity:	70/298 - (23%)
Similarity:	108/298 - (36%)	Gaps:	89/298 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 AAAPDPLGIDELMSASDIKIEPIQLQMEEDPQAPYPENQLEQALSYGNAPGEDILPLPEDYGEAQ 163
            |:.|.|       :||:.|      .:|.|| ||     |.:.|.....    :|..|::.  |:
  Fly   248 ASMPPP-------AASETK------PLEVDP-AP-----LHKCLDCNGL----LLETPDEV--AK 287

  Fly   164 TEVA------TTTNEPAQRRSKNTAKIKS--KKH-----------------TMRVGRKLIHVKVI 203
            .|.|      |......||..:..|.:|.  |.|                 .:::|...:|.|:.
  Fly   288 HEAAAHRLRLTYRCSECQREFELLAGLKKHLKTHRTEGRKDTWKKCPDCGKCLKLGSMWMHRKIH 352

  Fly   204 DDKQP-------KRIVD--------RNGPSAKPCICEHCGRQFKDTSNLHVHLLRHTGTKPFECD 253
            .|.:.       ::.|.        |...|.||..|..|.::|::.|:|..|...|..|:.:.|:
  Fly   353 SDNKKYQCDICGQKFVQKINLTHHARIHSSEKPYECPECQKRFQERSHLQRHQKYHAQTRSYRCE 417

  Fly   254 QCHQKCYTLHLLRRHQLKHTE-GPYACTFCGLEYSTNSSRVRHEREACKKGRAPQSKWEIIKKGE 317
            :|.:...|...|:.|.|.|.| .|:|||.|...:.:||...:|..               |..|.
  Fly   418 KCGKMYKTERCLKVHNLVHLEQRPFACTVCDKSFISNSKLKQHSN---------------IHTGM 467

  Fly   318 RTFHCEVCDLWFLRAGNFTQHI--------NSSSHIEN 347
            |.|.|..|...|....|:.:|.        .:..|:||
  Fly   468 RPFKCNYCPRDFTNFPNWLKHTRRRHKVDHKTGEHLEN 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4820	NP_001097748.1	zf-AD	4..75	CDD:285071
		C2H2 Zn finger	224..244	CDD:275368	6/19 (32%)
		C2H2 Zn finger	252..272	CDD:275368	6/19 (32%)
		C2H2 Zn finger	279..297	CDD:275368	6/17 (35%)
		C2H2 Zn finger	322..339	CDD:275368	4/16 (25%)
wdn	NP_476900.1	C2H2 Zn finger	301..321	CDD:275368	5/19 (26%)
		RPB9	333..425	CDD:224510	19/91 (21%)
		C2H2 Zn finger	333..352	CDD:275368	3/18 (17%)
		zf-H2C2_2	344..369	CDD:290200	3/24 (13%)
		zf-C2H2	358..380	CDD:278523	2/21 (10%)
		C2H2 Zn finger	360..380	CDD:275368	2/19 (11%)
		zf-H2C2_2	372..395	CDD:290200	6/22 (27%)
		zf-C2H2	386..408	CDD:278523	6/21 (29%)
		C2H2 Zn finger	388..436	CDD:275368	14/47 (30%)
		zf-H2C2_2	400..425	CDD:290200	6/24 (25%)
		C2H2 Zn finger	416..433	CDD:275368	4/16 (25%)
		zf-H2C2_2	429..453	CDD:290200	10/23 (43%)
		C2H2 Zn finger	444..464	CDD:275368	6/34 (18%)
		zf-H2C2_2	457..481	CDD:290200	8/38 (21%)
		C2H2 Zn finger	472..493	CDD:275368	5/20 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457197
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930