DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4820 and CG4854

DIOPT Version :9

Sequence 1:	NP_001097748.1	Gene:	CG4820 / 41344	FlyBaseID:	FBgn0037876	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	NP_650860.1	Gene:	CG4854 / 42391	FlyBaseID:	FBgn0038766	Length:	319	Species:	Drosophila melanogaster

Alignment Length:	364	Identity:	92/364 - (25%)
Similarity:	138/364 - (37%)	Gaps:	75/364 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 CRTCGKTVVADECLQIFTP-AGRKLLQCVRSITNCWLQNVQDLPNHICTDCQVLLSQVQKFRRRC 68
            ||.| .....||.|....| ...|:.:|    |...|....|.||.|||.|.:||....|.|..|
  Fly    12 CRIC-LVQPKDESLMPTEPDFPDKIKRC----TGVELSESPDWPNRICTSCALLLRAALKLRSLC 71

  Fly    69 AKIEKYFARRR-RRMNL---GEAPAAMEQLRVQQAAAPDPLGIDELMSASDIKIEPIQLQMEEDP 129
            .:.||....:: :.:|:   .:.....::...:..:..:..|.|..:....:....:.|:..||.
  Fly    72 QQTEKDLKEQKLQEINIEIVHDEQETKKKTESRDLSKNEATGSDSELEYEYLDSYDVTLESSEDV 136

  Fly   130 QAPYPE-NQLEQALSYGNAPGEDIL---PLP-----EDYGEAQTEVATTTNEPAQRRSKNTAKIK 185
            .....| ..:|.|:|   ||.|.:.   |.|     ||.|:|.:......|.....|.|.|.
  Fly   137 ACSADELVSIEPAIS---APEESVYSLSPKPVTFEDEDSGQAASFTCNICNNVYSERVKLTN--- 195

  Fly   186 SKKHTMRVGRKLIHVKVIDDKQPKRIVDRNGPSAKPCICEHCGRQFKDTSNLHVHLLRHTGTKPF 250
                         |:||...|:|..             ||.|.::|:.|..|..|:..|||.:|:
  Fly   196 -------------HMKVHSAKKPHE-------------CEICHKRFRQTPQLARHMNTHTGNRPY 234

  Fly   251 ECDQCHQKCYTLHLLRRHQLKHT-EGPYACTFCGLEYS-TNSSRVRHEREACKKGRAPQSKWEII 313
            :||.|..:........:||..|| |.||.|.||...:. :|..||..:...
  Fly   235 KCDYCDSRFADPSTRIKHQRIHTNERPYKCEFCSRSFGYSNVLRVHLKTHT-------------- 285

  Fly   314 KKGERTFHCEVCDLWFLRAGNFTQHINSSSHIENERRKK 352
              |||.|.|:.|.      .:|:|..:.:||.::.:|.|
  Fly   286 --GERPFSCQYCQ------KSFSQLHHKNSHEKSHKRTK 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4820	NP_001097748.1	zf-AD	4..75	CDD:285071	25/70 (36%)
		C2H2 Zn finger	224..244	CDD:275368	7/19 (37%)
		C2H2 Zn finger	252..272	CDD:275368	5/19 (26%)
		C2H2 Zn finger	279..297	CDD:275368	6/18 (33%)
		C2H2 Zn finger	322..339	CDD:275368	4/16 (25%)
CG4854	NP_650860.1	zf-AD	12..>57	CDD:285071	17/49 (35%)
		C2H2 Zn finger	180..200	CDD:275368	6/35 (17%)
		zf-H2C2_2	193..217	CDD:290200	10/52 (19%)
		COG5048	201..>258	CDD:227381	19/69 (28%)
		C2H2 Zn finger	208..228	CDD:275368	7/19 (37%)
		zf-H2C2_2	221..244	CDD:290200	9/22 (41%)
		C2H2 Zn finger	236..256	CDD:275368	5/19 (26%)
		zf-H2C2_2	251..273	CDD:290200	10/21 (48%)
		C2H2 Zn finger	264..284	CDD:275368	6/19 (32%)
		zf-H2C2_2	277..301	CDD:290200	9/45 (20%)
		C2H2 Zn finger	292..312	CDD:275368	6/25 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.050