DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4820 and CG17801

DIOPT Version :9

Sequence 1:	NP_001097748.1	Gene:	CG4820 / 41344	FlyBaseID:	FBgn0037876	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	NP_650660.2	Gene:	CG17801 / 42144	FlyBaseID:	FBgn0038550	Length:	381	Species:	Drosophila melanogaster

Alignment Length:	403	Identity:	97/403 - (24%)
Similarity:	162/403 - (40%)	Gaps:	94/403 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 CRTC----GKTVVADECLQIFTPAGRKLLQCVRSITNCWLQNVQDLPNHICTDCQVLLSQVQKFR 65
            |.:|    ..|::.  ||::        |..::.:|..||:..:..|.|||..|...|:...|.:
  Fly    13 CASCFCHLNPTIIF--CLEV--------LAKIKDLTGIWLEQNERQPRHICPSCLNDLNTSIKLK 67

  Fly    66 RRCAKIEKYFARRRRRMNLGEAPAAMEQLRVQQAAAPDPLGIDELMSASDIKIEP----IQLQME 126
            :|..::......||..                        |:||.:.::...|||    ..|:.|
  Fly    68 KRIQRVHNEATLRRES------------------------GLDEDLESTVSDIEPEGDSSDLESE 108

  Fly   127 EDPQAP-YP------ENQLEQALSYGNA------PGEDILPLPEDYGEAQTEVATTTNEPAQRRS 178
            |...:. ||      |:.::..|::.:.      |.:...||...:.....|..:..||  ...:
  Fly   109 ESYDSENYPFDKKAEESDIDLNLAHEDRRNEPHNPYDSETPLIFKHKNPLIETPSFANE--NLPN 171

  Fly   179 KNTAKIKSKKHTMRVGRKL------IHVKVIDD--KQPKRIVDRNGPSAK-------PCICEHCG 228
            |..||...|.:.:::|..|      ..:||:..  ..|:.:...|.|.||       ..:|..||
  Fly   172 KVDAKSPKKGNFIQIGTDLRLLTTYPSIKVVKPLALAPEDVAAENVPPAKRTARKMQSLVCPKCG 236

  Fly   229 RQFKDTSNLHVHLLRHTGTKPFECDQCHQKCYTLHLLRRHQ-LKHT-EGPYACTFCGLEYSTNSS 291
            |.||...||..|::||||.|.|.|..|.::..|.:|.|.|: ::|. |.|:.|.||...:.|:::
  Fly   237 RVFKTPYNLKTHMVRHTGEKNFPCTFCDKRFVTKYLARLHERVRHMGEQPFECNFCSATFFTSTA 301

  Fly   292 RVRHER-----------EACKK---GRAPQSKWEIIKKGERTFHCEVCDLWFLRAGNFTQHINSS 342
            :..|||           :.|.|   .:...:|.:.:..|.:.|.|.:|.:.|.|......|.:|.
  Fly   302 KSSHERIRHIRDLRYQCDQCTKRFNTKTCLNKHKFLHSGLKPFDCVICQINFARKATLRSHFDSV 366

  Fly   343 SHIENERRKKRKS 355
            :|      :||.|
  Fly   367 AH------QKRAS 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4820	NP_001097748.1	zf-AD	4..75	CDD:285071	17/73 (23%)
		C2H2 Zn finger	224..244	CDD:275368	9/19 (47%)
		C2H2 Zn finger	252..272	CDD:275368	6/20 (30%)
		C2H2 Zn finger	279..297	CDD:275368	5/17 (29%)
		C2H2 Zn finger	322..339	CDD:275368	4/16 (25%)
CG17801	NP_650660.2	zf-AD	9..74	CDD:285071	17/70 (24%)
		zf-C2H2	231..252	CDD:278523	9/20 (45%)
		C2H2 Zn finger	232..252	CDD:275368	9/19 (47%)
		zf-H2C2_2	244..269	CDD:290200	11/24 (46%)
		C2H2 Zn finger	260..281	CDD:275368	6/20 (30%)
		C2H2 Zn finger	289..308	CDD:275368	6/18 (33%)
		C2H2 Zn finger	318..338	CDD:275368	3/19 (16%)
		C2H2 Zn finger	346..362	CDD:275368	4/15 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_120097
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.860