DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4820 and CG17802

DIOPT Version :9

Sequence 1:	NP_001097748.1	Gene:	CG4820 / 41344	FlyBaseID:	FBgn0037876	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	NP_650659.2	Gene:	CG17802 / 42143	FlyBaseID:	FBgn0038549	Length:	439	Species:	Drosophila melanogaster

Alignment Length:	422	Identity:	111/422 - (26%)
Similarity:	178/422 - (42%)	Gaps:	87/422 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 CRTCGKTVVADECLQIFTPAGRKLLQCVRSITNCWLQNVQDLPNHICTDCQVLLSQVQKFRRRCA 69
            ||.||..:.....:.|| ....|:::.:..:|..||.:...:|.::|:.|.:.|.....||:.|.
  Fly     5 CRLCGDLIYTQNPVNIF-DENSKMVRQIALVTGLWLTDHSKMPRNMCSCCLLSLKSAIAFRQACI 68

  Fly    70 KIEKYFARRRRRMN----------LGEA-------PAAMEQLRVQQAAAPDPLGIDE---LMSAS 114
            |.......:||.:.          |.:|       .|.:||..:.:.:..|..|::|   |....
  Fly    69 KTNNRLTIQRRSVEAKDDGCWADPLSDAHEGLKINDAEVEQEVLYEVSYADNEGLEEDHDLYKKE 133

  Fly   115 DIKIEPIQLQMEEDPQAPYP----ENQLEQALSY--------GNAPGE----------------- 150
            :.:.|..:.:..||.....|    :::.||...|        |:..||
  Fly   134 EEESEVNENKEFEDIACEIPFSKEDDEQEQQQEYEDMVDKKTGHDDGEESQECEESQPDEEESQQ 198

  Fly   151 ------------DILPLPEDYGEAQTEVATTTN-EPAQRRSK-NTAKIKSKKHTMRVGRKLIHVK 201
                        |.|...|| |::.|:..:.:: |...|:|. :..|...:|:|.|...|.....
  Fly   199 NEEDEEESQEDDDELWQNED-GDSDTDADSMSDIEATSRQSALDEDKKPRRKYTKRSSPKNDDTD 262

  Fly   202 VIDDKQPKRIVDRNGPSAKPCICEHCGRQFKDTSNLHVHLLRHTGTKPFECDQCHQKCYTLHLLR 266
            .:...:.||   :...|.|..||:|||::|.|..|.::|:|||:|.|||||.:|.||.:..::|.
  Fly   263 FLKPAKKKR---KTYISQKVHICDHCGKKFTDKGNFNLHVLRHSGVKPFECPECGQKEFNRYILN 324

  Fly   267 RH-QLKHT-EGPYACTFCGLEYSTNSSRVRHEREACKKGRAP-----------------QSKWEI 312
            .| ::||. |.||||.||...:..::.|.|||....:..:.|                 ::|.|:
  Fly   325 IHIRVKHRGEKPYACQFCDERFVHSTMRSRHENRVHRNKKTPKNFKCNYCDKRYESNYQRAKHEV 389

  Fly   313 IKKGERTFHCEVCDLWFLRAGNFTQHINSSSH 344
            :..|||.||||||.:.|.|..|...|..|..|
  Fly   390 VHTGERNFHCEVCKVSFTRNSNLKTHYRSRQH 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4820	NP_001097748.1	zf-AD	4..75	CDD:285071	18/69 (26%)
		C2H2 Zn finger	224..244	CDD:275368	9/19 (47%)
		C2H2 Zn finger	252..272	CDD:275368	6/20 (30%)
		C2H2 Zn finger	279..297	CDD:275368	6/17 (35%)
		C2H2 Zn finger	322..339	CDD:275368	7/16 (44%)
CG17802	NP_650659.2	zf-AD	4..74	CDD:285071	18/69 (26%)
		C2H2 Zn finger	282..302	CDD:275368	9/19 (47%)
		C2H2 Zn finger	310..331	CDD:275368	6/20 (30%)
		C2H2 Zn finger	339..360	CDD:275368	7/20 (35%)
		C2H2 Zn finger	371..388	CDD:275370	1/16 (6%)
		zf-met	398..421	CDD:289631	10/22 (45%)
		C2H2 Zn finger	399..417	CDD:275368	8/17 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_120097
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.860