DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4820 and ranshi

DIOPT Version :9

Sequence 1:	NP_001097748.1	Gene:	CG4820 / 41344	FlyBaseID:	FBgn0037876	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster

Alignment Length:	382	Identity:	104/382 - (27%)
Similarity:	166/382 - (43%)	Gaps:	77/382 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 CRTCGKTVVADECLQIFTPAGRKLLQCVRSITNCWLQNVQDLPNHICTDCQVLLSQVQKFRRRCA 69
            ||||||...|:..|.||....:..|:.::.:|...|:|...|||.:|..||..|.|...||.||.
  Fly     6 CRTCGKRTNAERSLNIFEKRNQTTLEHIKLLTGAVLKNCSTLPNRLCASCQTCLQQAISFRERCL 70

  Fly    70 KIEKYFARRRRRMNL----GEAP-AAMEQLRVQQAAAPDPLGIDEL-------MSASDIKIEPI- 121
            ::::.....:...:.    .|:| :.:||..::...|...:.::.|       :.:|..|:|.|
  Fly    71 EVQRELLHSQDDEDFLRICQESPKSVLEQEELELDLAEISIEVERLDDLNEGPIQSSGFKVEDIL 135

  Fly   122 -QLQMEEDPQAPYPENQLEQALSYGNAPGEDILPLPEDYGEAQTEVATTTNEPAQRRSKNTAKIK 185
             :.::.||.    |.|:            :||     ||.|....:..:..|...::     ::|
  Fly   136 NESKINEDE----PNNE------------DDI-----DYSEMDYLIYESDTEVDAKQ-----ELK 174

  Fly   186 SKKHTMRVGRKLIHVKVIDDKQPKRIVDRNGP--SAKPCICEHCGRQFKDTSNLHVHLLRHTGTK 248
            |                 |.:.||:..:|..|  |.:...||.||...||..:..:|..||.|.|
  Fly   175 S-----------------DSENPKKRRNRRNPRDSNRTFFCEECGNHIKDRISFILHCKRHRGVK 222

  Fly   249 PFECDQCHQKCYTLHLLRRHQLKHT-EGPYACTFCGLEYSTNSSRVRHERE-------ACKKGRA 305
            .|.|:.|..:..|...|:||..||| |.|:.|..|...:|..|:|::|||.       .||:...
  Fly   223 EFGCEFCEDRFCTPAELKRHIRKHTGEKPFKCRHCSRSFSDYSTRLKHERTHTNERPFVCKECNN 287

  Fly   306 PQSKWEIIKK------GERTFHCEVCDLWFLRAGNFTQHINSSSHIENERRKKRKSN 356
            ..:...|:|.      ||:.|.|::||..|.|..:.|.|..|::|    ||..:|::
  Fly   288 AFTTSYILKNHMLVHTGEKAFRCDLCDKLFSRYTHLTTHYRSNAH----RRNMQKAD 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4820	NP_001097748.1	zf-AD	4..75	CDD:285071	26/69 (38%)
		C2H2 Zn finger	224..244	CDD:275368	7/19 (37%)
		C2H2 Zn finger	252..272	CDD:275368	6/19 (32%)
		C2H2 Zn finger	279..297	CDD:275368	6/17 (35%)
		C2H2 Zn finger	322..339	CDD:275368	6/16 (38%)
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	26/70 (37%)
		C2H2 Zn finger	198..218	CDD:275368	7/19 (37%)
		COG5048	222..>276	CDD:227381	21/53 (40%)
		C2H2 Zn finger	226..246	CDD:275368	6/19 (32%)
		zf-H2C2_2	238..262	CDD:290200	10/23 (43%)
		C2H2 Zn finger	254..274	CDD:275368	8/19 (42%)
		zf-H2C2_2	269..291	CDD:290200	5/21 (24%)
		C2H2 Zn finger	282..302	CDD:275368	4/19 (21%)
		zf-H2C2_2	295..319	CDD:290200	8/23 (35%)
		C2H2 Zn finger	310..328	CDD:275368	7/17 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_120097
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.860