DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4820 and ouib

DIOPT Version :9

Sequence 1:	NP_001097748.1	Gene:	CG4820 / 41344	FlyBaseID:	FBgn0037876	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	NP_649822.2	Gene:	ouib / 41039	FlyBaseID:	FBgn0037618	Length:	312	Species:	Drosophila melanogaster

Alignment Length:	376	Identity:	88/376 - (23%)
Similarity:	140/376 - (37%)	Gaps:	98/376 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 CRTCGKTVVADECLQIFTPAGRKLLQCVRSITNCWLQNVQDLPNHICTDCQVLLSQVQKFRRRCA 69
            ||.||:..:.::.|.:|....||.|:.:..|:...|.::.|:|..:|..||..|.....||:.|.
  Fly     6 CRVCGRQKICEKSLNLFDLVNRKYLKHLHMISGLRLVDLDDVPGFMCLCCQAELRSALAFRKLCI 70

  Fly    70 KIE-KYFARRRRRMNLGEAPAAMEQLRVQQAAAPDPLG-------IDELMSASDIKIEPIQLQME 126
            |.: |:........:..|......:|..::.|..| .|       ::|..... |:.||:...:.
  Fly    71 KTQTKWLTIEDDSSSGDEDTNDNSELESEKCAFSD-FGKKKEGELVEETFQVL-IEEEPMDKTLN 133

  Fly   127 EDPQAPYPENQLEQALSYGNAPGEDILPLPEDYGEAQTEVATTTNEPAQRRSKNTAKIKSKKHTM 191
            .|.:|...|:.::          |..:|                       |:...|:.:|
  Fly   134 RDAKAQLREDGID----------EKCVP-----------------------SQKIIKVSTK---- 161

  Fly   192 RVGRKLIHVKVIDDKQPKRIVDRNGPSAKPCICEHCGRQFKDTSNLHVHLLRHTGTKPFECDQCH 256
                       :||              :..|||.||...........|:.:|.|.:||.|..|.
  Fly   162 -----------LDD--------------QIYICELCGTHATSKPTFQRHMRKHRGERPFGCKDCD 201

  Fly   257 QKCYTLHLLRRHQLKHT-EGPYACTFCGLEYSTNSSRVRHER----------EACKKGRAPQSKW 310
            .:..:...||.|...|| |.|:||.||...|.:...|:.|||          |.|.|      |:
  Fly   202 ARFLSAGELRAHHRVHTGEQPFACRFCEKRYVSYMGRLIHERTHTNDRPYVCEECGK------KF 260

  Fly   311 E---------IIKKGERTFHCEVCDLWFLRAGNFTQHINSSSHIENERRKK 352
            .         :|..|||.|.|::||..|.|..:...|..|..|::|.:::|
  Fly   261 TTAYVLKNHMVIHTGERNFRCDICDRSFQRKAHLVTHTRSMMHLQNVKKQK 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4820	NP_001097748.1	zf-AD	4..75	CDD:285071	22/70 (31%)
		C2H2 Zn finger	224..244	CDD:275368	5/19 (26%)
		C2H2 Zn finger	252..272	CDD:275368	5/19 (26%)
		C2H2 Zn finger	279..297	CDD:275368	6/17 (35%)
		C2H2 Zn finger	322..339	CDD:275368	5/16 (31%)
ouib	NP_649822.2	zf-AD	5..78	CDD:214871	22/71 (31%)
		COG5048	<158..300	CDD:227381	46/176 (26%)
		C2H2 Zn finger	169..189	CDD:275368	5/19 (26%)
		C2H2 Zn finger	197..217	CDD:275368	5/19 (26%)
		zf-H2C2_2	209..234	CDD:290200	12/24 (50%)
		C2H2 Zn finger	225..245	CDD:275368	8/19 (42%)
		zf-H2C2_2	241..262	CDD:290200	7/26 (27%)
		C2H2 Zn finger	253..273	CDD:275368	4/25 (16%)
		zf-H2C2_2	266..288	CDD:290200	8/21 (38%)
		C2H2 Zn finger	281..299	CDD:275368	6/17 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_120097
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.860