DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4820 and nom

DIOPT Version :9

Sequence 1:	NP_001097748.1	Gene:	CG4820 / 41344	FlyBaseID:	FBgn0037876	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	NP_001262384.1	Gene:	nom / 41038	FlyBaseID:	FBgn0037617	Length:	370	Species:	Drosophila melanogaster

Alignment Length:	402	Identity:	87/402 - (21%)
Similarity:	147/402 - (36%)	Gaps:	123/402 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 CRTCGKTVVADECLQIFTPAGRKLLQCVRSITNCWLQNVQDLPNHICTDCQVLLSQVQKFRRRCA 69
            ||.||::.:..:.:::|.|..:.:|:.::.||...||.:.:.|:.:|..||..|.....|||:|.
  Fly     6 CRVCGRSRLCPKAVELFKPGRQDILRRIQLITGILLQQIPNAPDMVCFCCQTDLQSAMIFRRQCI 70

  Fly    70 KIEKYFARRRRRMNLGEAPAAMEQLRVQQAAAPDPLGIDELMSASDIKIEPIQLQMEEDPQAP-- 132
                                      :||......|..|::.::.:.|:||      .||...
  Fly    71 --------------------------LQQKKWVPLLQSDKVGASEEKKVEP------NDPSTKKK 103

  Fly   133 -------YPENQL---------EQALSYGNAPGEDILPLPEDYGEAQTEVATTTNEPAQRRSKNT 181
                   .|...|         |...|.|.:.|.|....|.:          .:|||....|.
  Fly   104 TTKRRRGRPRMPLEIVDIVVTNESKASAGESVGGDEFDQPVE----------ISNEPDATDSD-- 156

  Fly   182 AKIKSKKHTMRVGRKLIHVKVIDDKQPKRIVDRNG-------PSAKPCICEHCGRQFKDTSNLHV 239
                            ::::.||      :.|.:|       |:.:...|:.||....:.|:|..
  Fly   157 ----------------VNLEEID------LPDEDGLESDHDLPNVQIHKCDTCGIIKNNKSSLVR 199

  Fly   240 HLLRHTGTKPFECDQCHQKCYTLHLLRRHQLKH--TEGPYACTFCGLEYSTNSSRVRHER----- 297
            |...|.|.:|:.|.:|.:.......|:.|.|.|  .|.|:||.:|...|.:...|.:|||
  Fly   200 HQFEHNGIRPYPCKECPKTFLVASELKAHNLTHHTLEPPFACRYCDRRYFSVVGRKKHERVHTNE 264

  Fly   298 -----EACKKG-------RAPQSKWEIIKKGERTFHCEVCDLWFLRAGNFTQHINSSSHIENERR 350
                 :.|.|.       :|..:..::::|    :.|:|||..|....:...|..|::|
  Fly   265 RPFVCDQCGKAFTRTCILKAHMAVHQVVRK----YSCDVCDRSFSLKKHLATHFISNTH------ 319

  Fly   351 KKRKSNPTAINS 362
               |.|..|:.|
  Fly   320 ---KRNAEAVTS 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4820	NP_001097748.1	zf-AD	4..75	CDD:285071	20/69 (29%)
		C2H2 Zn finger	224..244	CDD:275368	6/19 (32%)
		C2H2 Zn finger	252..272	CDD:275368	5/19 (26%)
		C2H2 Zn finger	279..297	CDD:275368	5/17 (29%)
		C2H2 Zn finger	322..339	CDD:275368	5/16 (31%)
nom	NP_001262384.1	zf-AD	5..76	CDD:214871	22/95 (23%)
		C2H2 Zn finger	184..204	CDD:275368	6/19 (32%)
		C2H2 Zn finger	212..261	CDD:275368	16/48 (33%)
		zf-H2C2_2	255..278	CDD:290200	5/22 (23%)
		C2H2 Zn finger	269..289	CDD:275368	3/19 (16%)
		zf-H2C2_2	282..305	CDD:290200	6/26 (23%)
		C2H2 Zn finger	297..313	CDD:275368	5/15 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_120097
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.860