DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4820 and MTF-1

DIOPT Version :9

Sequence 1:	NP_001097748.1	Gene:	CG4820 / 41344	FlyBaseID:	FBgn0037876	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	NP_001097560.1	Gene:	MTF-1 / 39089	FlyBaseID:	FBgn0040305	Length:	1006	Species:	Drosophila melanogaster

Alignment Length:	287	Identity:	66/287 - (22%)
Similarity:	106/287 - (36%)	Gaps:	74/287 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 IKIEP---IQLQMEEDP-QAPYPENQLEQALSYGNAPGEDILPLPEDYGEAQTEVAT--TTNEPA 174
            ::::|   :.|.|...| :|..|....:.....||:...|.......|...:|....  ..|||.
  Fly   218 VQVQPPTVVSLSMVSSPNEAANPPINCDNDQGTGNSISRDSTSNSPAYFTIETSYVDEYDPNEPD 282

  Fly   175 QRRSKNTAKIKSKKHTMRVGRKLIHVKVIDDKQPKRIVDRNGP-------------SAKPCICEH 226
            :.        :...|.::.|  ::| :.:|:::.:| .|.|..             |...|..|:
  Fly   283 ED--------EQLAHCIQPG--VLH-QDVDEEEVER-QDENDQLMALAYESSDEALSRYRCNYEN 335

  Fly   227 CGRQFKDTSNLHVHLLRHTGTKPFEC--DQCHQKCYTLHLLRRHQLKHTE-GPYACTFCGLEYST 288
            |.|.:....||..||..|||...|:|  |.||:...|.:.|:.|...||: .||.|...|.:.:.
  Fly   336 CYRSYSTIGNLRTHLKTHTGDYSFKCPEDGCHKAFLTSYSLKIHVRVHTKVKPYECEVSGCDKAF 400

  Fly   289 NSSRVR---HEREACKKGRAPQSKWEIIKKGERTFHCEVCDLWFLRAGNFTQHI----------- 339
            | :|.|   |.|               :..|| ||:||:|...|....:..:|:
  Fly   401 N-TRYRLHAHLR---------------LHNGE-TFNCELCQKCFTTLSDLKKHMRTHTQERPYKC 448

  Fly   340 ---------NSSSHIENERRKKRKSNP 357
                     .:|.|::..||......|
  Fly   449 PEDDCGKAFTASHHLKTHRRTHTGEKP 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4820	NP_001097748.1	zf-AD	4..75	CDD:285071
		C2H2 Zn finger	224..244	CDD:275368	7/19 (37%)
		C2H2 Zn finger	252..272	CDD:275368	7/21 (33%)
		C2H2 Zn finger	279..297	CDD:275368	6/20 (30%)
		C2H2 Zn finger	322..339	CDD:275368	4/16 (25%)
MTF-1	NP_001097560.1	zf-C2H2_aberr	329..471	CDD:293622	43/158 (27%)
		C2H2 Zn finger	331..353	CDD:275368	8/21 (38%)
		zf-H2C2_2	345..372	CDD:290200	12/26 (46%)
		C2H2 Zn finger	361..383	CDD:275368	7/21 (33%)
		zf-H2C2_2	375..402	CDD:290200	9/27 (33%)
		C2H2 Zn finger	391..413	CDD:275368	7/37 (19%)
		zf-C2H2	418..440	CDD:278523	6/21 (29%)
		C2H2 Zn finger	420..440	CDD:275368	5/19 (26%)
		zf-H2C2_2	432..458	CDD:290200	1/25 (4%)
		COG5048	442..>519	CDD:227381	5/34 (15%)
		C2H2 Zn finger	448..470	CDD:275368	4/21 (19%)
		zf-H2C2_2	462..489	CDD:290200	4/14 (29%)
		C2H2 Zn finger	478..500	CDD:275368
		DUF3682	862..>931	CDD:289231
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457144
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930