DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4820 and pita

DIOPT Version :9

Sequence 1:	NP_001097748.1	Gene:	CG4820 / 41344	FlyBaseID:	FBgn0037876	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	NP_611806.3	Gene:	pita / 37730	FlyBaseID:	FBgn0034878	Length:	683	Species:	Drosophila melanogaster

Alignment Length:	425	Identity:	93/425 - (21%)
Similarity:	154/425 - (36%)	Gaps:	111/425 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 KEFCRTCGKTVVADECLQIFTPAGRKLLQCVRSITNCWLQNV----------QDLPNHICTDCQV 56
            |..||.|   :...:...||....|     |::..|..||.:          ..:|.|||.:|::
  Fly    15 KRVCRFC---LTEQKLASIFEENPR-----VKTTANLPLQIMAITAIEVYAGDGMPGHICLECRL 71

  Fly    57 LLSQVQKFRRRCAKIEKYFARRRRRMNLGEAPAAMEQLR------------------VQQAAAPD 103
            |.....:|::.|.:.|...   |:....|..|:.:|:.|                  .:.:..|.
  Fly    72 LFEHCYRFKQMCKRAETLL---RQYPLTGNWPSPLEKPRAPMTMVASKKLLVVPAKTAEPSETPK 133

  Fly   104 PLGIDELMSASDIKIEPIQLQMEE---DPQ-----APYPENQLEQALSYGN---APGEDILPLPE 157
            .|......|:|.:.||.:|: :|.   .|:     :|.|.......|...|   ...:|:..:.|
  Fly   134 KLLNTMAKSSSQVIIEDVQV-LESAMVTPRTVAGSSPVPRRSHAYELKVDNNQELSMDDVQSMLE 197

  Fly   158 DYGEAQTEVATTTNEPAQRRSKNTAKIKSKKHTMRV-----------------------GRKLIH 199
            |..   :|:.....:..|:.|....|:.:|. ::|:                       |...|.
  Fly   198 DMA---SELEKEFPDIPQKASPVKPKVLNKS-SIRILNKGPAAPVEPRLATPKVKRDDSGNVAIV 258

  Fly   200 VKVIDDKQPKRIVDRNGPSAK---------PCICEHCGRQFKDTSNLHVHLLRHTGTKPFECDQC 255
            .:|:|...|  :.|::.|:..         |  |..|.|.|.....|.:|.|.||.::.|:|..|
  Fly   259 TEVLDSDLP--LDDQDDPTKNAEKVATDVFP--CPDCERSFPLQQLLEIHRLNHTRSRSFQCLLC 319

  Fly   256 HQKCYTLHLLRRHQLKHT-EGPYACTFCGLEYSTNSSRVRHERE----------ACKKGRAP-QS 308
            .:..::.:.|.:|...|| |.|:.|..|...::..:...||||.          .|:|   | .|
  Fly   320 EKSFFSKYDLAKHNFVHTGERPFKCAICSKAFTRKALLHRHERTHTDVPKFICVYCEK---PFLS 381

  Fly   309 KWEIIKKGE-----RTFHCEVCDLWFLRAGNFTQH 338
            :.|:.|..|     |.|.|.||...|.......:|
  Fly   382 RQEMEKHAERHQKKRPFQCGVCTKSFAFKQGLERH 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4820	NP_001097748.1	zf-AD	4..75	CDD:285071	19/80 (24%)
		C2H2 Zn finger	224..244	CDD:275368	7/19 (37%)
		C2H2 Zn finger	252..272	CDD:275368	4/19 (21%)
		C2H2 Zn finger	279..297	CDD:275368	4/17 (24%)
		C2H2 Zn finger	322..339	CDD:275368	5/17 (29%)
pita	NP_611806.3	zf-AD	17..92	CDD:214871	19/85 (22%)
		COG5048	<281..506	CDD:227381	39/141 (28%)
		C2H2 Zn finger	288..308	CDD:275368	7/19 (37%)
		C2H2 Zn finger	316..336	CDD:275368	4/19 (21%)
		zf-H2C2_2	328..353	CDD:290200	8/24 (33%)
		C2H2 Zn finger	344..364	CDD:275368	6/19 (32%)
		C2H2 Zn finger	372..388	CDD:275370	5/18 (28%)
		C2H2 Zn finger	400..420	CDD:275368	5/17 (29%)
		C2H2 Zn finger	428..448	CDD:275368
		C2H2 Zn finger	456..476	CDD:275368
		C2H2 Zn finger	486..506	CDD:275368
		HARE-HTH	<566..625	CDD:294801
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.050