DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4820 and CG1603

DIOPT Version :9

Sequence 1:	NP_001097748.1	Gene:	CG4820 / 41344	FlyBaseID:	FBgn0037876	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	NP_001260778.1	Gene:	CG1603 / 35683	FlyBaseID:	FBgn0033185	Length:	586	Species:	Drosophila melanogaster

Alignment Length:	328	Identity:	65/328 - (19%)
Similarity:	119/328 - (36%)	Gaps:	83/328 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 RCAKIEKYFARRRRRMN----LGEAPAAMEQLRVQQAAAPDP------LGID-------ELMSAS 114
            |....|....|..|:.|    :.|....:|||.||...|.:.      :|:.       |.:|.:
  Fly   226 RSMAYEAIMERMDRKANVLFTVEELKKTLEQLHVQYTLALETKQRGKLVGLAARYFAKCEFLSVA 290

  Fly   115 ----------DIKIEPIQLQMEEDPQAPYPENQLEQAL--SYGNAPGEDILPLPEDYGEA----- 162
                      |..:..|:|..:|       ||.:..:.  :|.|.|......|| |:|..
  Fly   291 PVVTPRENEEDNDLTAIKLNFKE-------ENLITTSFIETYANYPVLYNQALP-DFGSIEIRAD 347

  Fly   163 ----------------QTEVATTTNEPAQRRSKNTAKIKSKKHTMRVGRKLIHVKVIDDKQPKRI 211
                            :|:|....|:..:.......::|||:...:..::.:....:....|.:
  Fly   348 AFKRMAKEFQPVVKANETDVYIAVNKLRRWLYDAIRRLKSKELIQKCSKQEVQYLQMCSFLPAK- 411

  Fly   212 VDRNGPSAKPCICEHCGRQFKDTSNLHVHLLR--HTGTKPFECDQCHQKCYTLHL-LRRHQLK-H 272
                |..::...|::|.::|....||.||:::  ..|..|:.|..|.:: :..|: :.||:|: |
  Fly   412 ----GSESQVLYCDYCDKRFHGDYNLRVHIVKAHEVGDLPYLCSFCPRR-FDRHVDMDRHKLRSH 471

  Fly   273 TEGPYACTFCGLEYSTNSSRVRHEREACKKGRAPQSKWEIIKKGERTFHCEVCDLWFLRAGNFTQ 337
            .|....|.:|...::.::....|               .:|..|||...|::|...|........
  Fly   472 FERKLKCQYCEKSFAVDTDLKVH---------------TLIHTGERPHVCDICGKTFRLKLLLDH 521

  Fly   338 HIN 340
            |:|
  Fly   522 HVN 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4820	NP_001097748.1	zf-AD	4..75	CDD:285071	2/7 (29%)
		C2H2 Zn finger	224..244	CDD:275368	7/21 (33%)
		C2H2 Zn finger	252..272	CDD:275368	6/21 (29%)
		C2H2 Zn finger	279..297	CDD:275368	3/17 (18%)
		C2H2 Zn finger	322..339	CDD:275368	3/16 (19%)
CG1603	NP_001260778.1	MADF_DNA_bdg	202..287	CDD:287510	14/60 (23%)
		GT1	321..408	CDD:304916	13/87 (15%)
		C2H2 Zn finger	420..441	CDD:275368	7/20 (35%)
		COG5048	<424..583	CDD:227381	27/117 (23%)
		C2H2 Zn finger	450..471	CDD:275368	6/21 (29%)
		C2H2 Zn finger	478..498	CDD:275368	3/34 (9%)
		zf-H2C2_2	490..513	CDD:290200	7/37 (19%)
		C2H2 Zn finger	506..527	CDD:275368	5/19 (26%)
		C2H2 Zn finger	535..555	CDD:275368
		C2H2 Zn finger	563..583	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457175
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930