DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4820 and wor

DIOPT Version :9

Sequence 1:	NP_001097748.1	Gene:	CG4820 / 41344	FlyBaseID:	FBgn0037876	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	NP_476601.1	Gene:	wor / 34906	FlyBaseID:	FBgn0001983	Length:	548	Species:	Drosophila melanogaster

Alignment Length:	405	Identity:	89/405 - (21%)
Similarity:	144/405 - (35%)	Gaps:	95/405 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 LLQCVRSITNCW-LQNV-QDLPNHICTDCQVLLSQVQKF---RRRCAKIEKYFARRRR----RMN 83
            ||:.:....:|. :||: :::|.         :...|.|   ....|:.|.....:||    .||
  Fly   166 LLKSIAEYEDCMKMQNIKEEIPP---------IPSPQLFYPPPTPLAEPEDLSVTQRRVLSENMN 221

  Fly    84 LGEAPAAMEQLRVQQAA---APDPLGIDELMSASDIKIEPIQLQMEEDPQAPYPENQL------- 138
            |.....|:  |.:|..|   ||.|:.::|.....||.    ||:::......|...|.
  Fly   222 LQNVARAL--LSMQHMAPQHAPPPIDMEEDQENQDIN----QLKIKSSNDLYYQCQQCNKCYATY 280

  Fly   139 ------EQALSYGNAPGEDILPLPEDYGEA--QTEVATTTNEPAQRRSKNTAKIKSKKHTMRVGR 195
                  :|..:|.:...:.|...|...|..  |||.. |....|..::.|.|..:|.:..:.|.|
  Fly   281 AGLVKHQQTHAYESTEYKIIRSQPGGSGAIVDQTEFC-TDQASALIQAANVASAQSMQKPVGVPR 344

  Fly   196 -------------------KLIHVKVIDDKQPKRI-----VDRNGPS-----------AKPCICE 225
                               :..|....:..|.|::     .|:...|           ..||.|.
  Fly   345 YHCQDCGKSYSTYSGLSKHQQFHCPSAEGNQVKKVFSCKNCDKTYVSLGALKMHIRTHTLPCKCP 409

  Fly   226 HCGRQFKDTSNLHVHLLRHTGTKPFECDQCHQKCYTLHLLRRHQLKHTE-GPYACTFCGLEYSTN 289
            .||:.|.....|..|:..|||.|||.|..|::.......||.|...|:: ..|:|..|...:|..
  Fly   410 ICGKAFSRPWLLQGHIRTHTGEKPFSCQHCNRAFADRSNLRAHMQTHSDVKKYSCPTCTKSFSRM 474

  Fly   290 SSRVRHEREAC--KKGRAPQSKWEIIKKGERTFHCEVCD-------LWFLRAGNFTQHINSSSHI 345
            |...:|.:..|  ::...|........:.:...|.:|.:       |::  ||:.     .||:.
  Fly   475 SLLAKHLQSGCQTEQSGGPSGSGGGFDQQQLQQHLQVYEEGHNPHQLYY--AGSV-----GSSNG 532

  Fly   346 ENERRKKRKSNPTAI 360
            |.|...:.:..|.||
  Fly   533 EEEEGGEYQMQPPAI 547

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4820	NP_001097748.1	zf-AD	4..75	CDD:285071	10/51 (20%)
		C2H2 Zn finger	224..244	CDD:275368	6/19 (32%)
		C2H2 Zn finger	252..272	CDD:275368	5/19 (26%)
		C2H2 Zn finger	279..297	CDD:275368	5/17 (29%)
		C2H2 Zn finger	322..339	CDD:275368	4/23 (17%)
wor	NP_476601.1	C2H2 Zn finger	270..290	CDD:275368	2/19 (11%)
		C2H2 Zn finger	317..334	CDD:275368	4/17 (24%)
		zf-C2H2	345..367	CDD:278523	0/21 (0%)
		C2H2 Zn finger	347..367	CDD:275368	0/19 (0%)
		PHA00732	379..>417	CDD:177300	8/37 (22%)
		C2H2 Zn finger	382..402	CDD:275368	2/19 (11%)
		zf-C2H2_8	405..482	CDD:292531	26/76 (34%)
		zf-C2H2	406..428	CDD:278523	7/21 (33%)
		C2H2 Zn finger	408..428	CDD:275368	6/19 (32%)
		zf-H2C2_2	421..444	CDD:290200	10/22 (45%)
		zf-C2H2	434..456	CDD:278523	6/21 (29%)
		C2H2 Zn finger	436..456	CDD:275368	5/19 (26%)
		zf-H2C2_2	448..473	CDD:290200	7/24 (29%)
		C2H2 Zn finger	464..481	CDD:275368	4/16 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457208
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930