Protein Alignment CG4820 and ZNF281

DIOPT Version :10

• Sequence 1: NP_001097748.1
• Gene: CG4820 / 41344
• FlyBaseID: FBgn0037876
• Length: 362
• Species: Drosophila melanogaster
• Sequence 2: NP_036614.1
• Gene: ZNF281 / 23528
• HGNCID: 13075
• Length: 895
• Species: Homo sapiens
• Alignment Length: 249
• Identity: 62/249 - (24%)
• Similarity: 95/249 - (38%)
• Gaps: 83/249 - (33%)

  Fly   170 TNEPAQRRSKNTAK--------IKSKKHTMRVGRKLIHVKVIDDKQPKRIVDRNG----PSAKPC 222
            |.||.|..:...||        ||:|:            |.....:|..:.|..|    ||.||.
Human   209 TEEPKQDTNVKKAKRPKPESQGIKAKR------------KPSASSKPSLVGDGEGAILSPSQKPH 261

  Fly   223 ICEHCGRQFKDTSNLHVHLLRHTGTKPFECDQCHQKCYTLHLLRRHQLKHT-EGPYACTFCGLEY 286
            ||:||...|:.:.:|..|:|.|||.:||:|.||.......:||:||:..|: |.|:.|..|.:::
Human   262 ICDHCSAAFRSSYHLRRHVLIHTGERPFQCSQCSMGFIQKYLLQRHEKIHSREKPFGCDQCSMKF 326

  Fly   287 STNSSRVRHEREACKKGRAPQSKWEIIKKGERTFHCEVCDLWFLRAGNFTQH------------- 338
            .......||:|               ...||:.:.|:.|..:|.|.....:|
Human   327 IQKYHMERHKR---------------THSGEKPYKCDTCQQYFSRTDRLLKHRRTCGEVIVKGAT 376

  Fly   339 ---INSSSH---------------------------IENERRKKRKSNPTAINS 362
               ..||:|                           |||:.:|..|:|.:.|::
Human   377 SAEPGSSNHTNMGNLAVLSQGNTSSSRRKTKSKSIAIENKEQKTGKTNESQISN 430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4820	NP_001097748.1	zf-AD	5..75	CDD:462262
		SUF4-like	224..>279	CDD:411020	22/55 (40%)
		C2H2 Zn finger	224..244	CDD:411020	7/19 (37%)
		C2H2 Zn finger	224..244	CDD:275368	7/19 (37%)
		C2H2 Zn finger	252..272	CDD:275368	7/19 (37%)
		C2H2 Zn finger	279..297	CDD:275368	4/17 (24%)
		C2H2 Zn finger	322..339	CDD:275368	5/32 (16%)
ZNF281	NP_036614.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..44
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..113
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	130..149
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	183..253		13/55 (24%)
		zf-C2H2_4	261..283	CDD:464025	8/21 (38%)
		C2H2 Zn finger	263..283	CDD:275368	7/19 (37%)
		zf-H2C2_2	275..300	CDD:463886	11/24 (46%)
		C2H2 Zn finger	291..311	CDD:275368	7/19 (37%)
		C2H2 Zn finger	319..339	CDD:275368	5/34 (15%)
		zf-H2C2_2	331..356	CDD:463886	8/39 (21%)
		C2H2 Zn finger	347..366	CDD:275368	5/18 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	377..427		9/49 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	638..660
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	778..817