Protein Alignment ZnT86D and COT1

DIOPT Version :9

• Sequence 1: NP_650049.1
• Gene: ZnT86D / 41342
• FlyBaseID: FBgn0037875
• Length: 366
• Species: Drosophila melanogaster
• Sequence 2: NP_014961.3
• Gene: COT1 / 854494
• SGDID: S000005843
• Length: 439
• Species: Saccharomyces cerevisiae
• Alignment Length: 378
• Identity: 111/378 - (29%)
• Similarity: 183/378 - (48%)
• Gaps: 59/378 - (15%)

  Fly    40 LLLNLSFAFVELFYGIVTNSLGLISDSFHMFFDCTGLLAGLAASVITKWKANDK-FSYGYVRAEV 103
            |||:..|..:|:..|.:::||.||:|||||..|...|:..|.|..:.|.:..|. ::||:.|||:
Yeast    14 LLLDTVFFGIEITTGYLSHSLALIADSFHMLNDIISLVVALWAVNVAKNRNPDSTYTYGWKRAEI 78

  Fly   104 LAGFVNSLFLLFIAFFILSEGVERLIEPPEVKHER-LFVVSVLGLLVNLVGIYAFNHGGHGHSHG 167
            |...:|::||:.:...||.|.::|:|.||.:::.: :..|.|.||:.|.||::.|:.....|.|
Yeast    79 LGALINAVFLIALCVSILIEALQRIIAPPVIENPKFVLYVGVAGLISNTVGLFLFHDNDQEHGH- 142

  Fly   168 GHGHSHGG---GH------GHGHSHGHTDA-------------------------GNHNHQAITL 198
            ||||||||   .|      .|.|:|.|.|.                         .|.|.:.:|.
Yeast   143 GHGHSHGGIFADHEMHMPSSHTHTHAHVDGIENTTPMDSTDNISEIMPNAIVDSFMNENTRLLTP 207

  Fly   199 DNGHGHSHDHDSHGHSHGDMSGSN---------SQIMRGVFLHILADTLGSVGVIISAVLMHM-- 252
            :|.   |........||...||.|         |..|.|||||:|.|.||::||::||..:..
Yeast   208 ENA---SKTPSYSTSSHTIASGGNYTEHNKRKRSLNMHGVFLHVLGDALGNIGVMLSAFFIWKTD 269

  Fly   253 FGW-MIADPICSIFIALLIALSVLSLIKESIMILMQRQPADLDRSLPQCYQKVTGLAGVYAVQEP 316
            :.| ...||:.|:.|..:|..|.|.|..::..||:|..|:.|  |..|....:..:.|:.|:.:.
Yeast   270 YSWKYYTDPLVSLIITGIIFSSALPLSCKASKILLQATPSTL--SGDQVEGDLLKIPGIIAIHDF 332

  Fly   317 HFWTLCSDVYVGALKLEVSKNVDPKYVVTHTRMI---FEAVGVKQIYIQLDYV 366
            |.|.|...:::.:|.:::  ::.|:......:::   ....|:....:|.:::
Yeast   333 HIWNLTESIFIASLHIQL--DISPEQFTDLAKIVRSKLHRYGIHSATLQPEFI 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZnT86D	NP_650049.1	CDF	46..366	CDD:273544	108/370 (29%)
		Cation_efflux	46..286	CDD:279834	93/287 (32%)
COT1	NP_014961.3	CzcD	9..384	CDD:224151	111/378 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1230
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG51881
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2014
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.850